Overview
Benzyl dichloride (α,α-dichlorotoluene) is an organochlorine compound primarily used as a reactive intermediate in chemical synthesis. Its molecular structure features two chlorine atoms bonded to a methylene group attached to a benzene ring, making it highly reactive in nucleophilic substitution reactions. Industrially, it is produced by free-radical chlorination of toluene under controlled conditions. As a lachrymator and corrosive substance, it requires careful handling. Its applications span pharmaceuticals (e.g., antihistamine synthesis), agrochemicals (pesticide precursors), and specialty chemicals. Global suppliers typically distribute it in 200kg steel drums or ISO tank containers for large-scale industrial buyers.
Physical and Chemical Properties
Benzyl dichloride exhibits a density of 1.26 g/cm³ at 20°C and boils at 205°C with decomposition. It emits toxic fumes (hydrogen chloride) when heated. The compound is hydrolytically unstable, reacting exothermically with water or moisture to form benzaldehyde and hydrochloric acid. Its IR spectrum shows characteristic C-Cl stretches at 740 cm⁻¹ and aromatic C-H bends near 3000 cm⁻¹. The electron-withdrawing effect of the chlorine atoms increases the electrophilicity of the benzylic carbon, enabling reactions with nucleophiles like amines or alkoxides. Compatibility testing is essential as it corrodes some plastics and rubbers.
Main Applications
In pharmaceuticals, benzyl dichloride serves as a precursor to benzyl alcohols and esters, which are building blocks for drugs like diphenhydramine. Agrochemical manufacturers use it to synthesize chlorinated pesticides and herbicides through Friedel-Crafts alkylation. The dye industry employs it to produce triarylmethane dyes, while fragrance companies utilize derivatives for musk compounds. Recent research explores its role in polymer chemistry as a crosslinking agent for specialty resins. China and India dominate production, with 70% output consumed regionally in API manufacturing.
Safety and Storage
Classified as Acute Toxin Category 3 (H301) and Skin Corrosion Category 1B (H314) under GHS, benzyl dichloride mandates strict controls. Storage requires inert atmospheres (nitrogen blanket) in corrosion-resistant containers (stainless steel/HDPE). Secondary containment is mandatory to prevent groundwater contamination from spills. Emergency protocols should include neutralization with sodium bicarbonate for small spills. Large leaks require professional hazmat teams. First aid measures involve immediate eye irrigation (15 minutes) and medical attention for inhalation exposure. Facilities handling >1 ton must comply with SARA Title III reporting in the US.
B2B Procurement Guide
Industrial buyers should prioritize suppliers with ISO 9001 certification and REACH registration. Key quality parameters include minimum 98% purity (GC analysis), low free chlorine content (<0.5%), and water content below 300 ppm. Request batch-specific COAs and third-party lab reports. Logistics considerations: Select freight providers experienced in hazardous chemical transport (UN 1886, Class 6.1). For international shipments, verify compliance with IMDG/IATA regulations. Negotiate contracts with flexibility for quarterly price adjustments linked to toluene feedstock costs. Sample testing is recommended before full container orders.
Related Manufacturers
- 主营：香豆素、铃兰花、家居香氛、绿色香料、结晶玫瑰、理想香料、甲基硝基胍、异丁酸苯酯、溴代十四烷、a 碳酸酯齐聚物、99%纯度新铃兰醛、聚脱氧核糖核酸、鲑鱼精、脱氧核糖核酸、四水合氟化镍、二苯并、邻氨基苯甲醇、L - 甲状腺素、蛋白胨、法尼醇、氰乙酸仲辛酯、52688-08-1、乙酸肉桂酯、十六烷基三甲基溴化铵、对甲苯磺酸
- 主营：5-溴-7-氮杂吲哚、柠檬酸钠、液体溴化钙
- 主营：四氢噻吩、三甲基戊烷、乙硫醇、二甲基亚砜、氧化三甲胺、环丁砜、正己烯、单氰胺、氟硅酸、氯乙酸、氯乙酸钠、叔丁硫醇、对叔丁基邻苯二酚、氟硼酸、溶剂油、乙硫氨酯、苯扎溴铵、三聚氯氰、亚磷酸三苯酯、对氟苯胺、正己烷、邻苯基苯酚、苯酚、叔十二硫醇、二甲基二硫醚
- 主营：架桥剂、YW100 锂萃取剂、端羧基液体丁腈橡胶、二氯三氟甲苯、10-羟基癸酸、苯乙烯磷酸、肉豆蔻酸镁、硬脂酸钴、全氟三丁胺、乙烯基磷酸二乙酯、磷酸锰铁锂、β-磷酸三钙、十一烯酸、钨酸铝、1-乙炔基环已醇、间二异丙苯、锂硅合金、溴甲酚绿、生物活性玻璃、溴代海因树脂颗粒、红铝、龙涎酮、原丁酸三甲酯
- 主营：甘氨酸、水苏糖、阻燃剂、间二氯苄、硫酸锌、硫酸锆、硫酸锂、硫酸锶、硫酸锰、铝酸锌、1680-21-3、牛磺酸、褪黑素、磷酸铁、丙酸铵、苏云金、碳酸镁、麝香酮、肉桂醛、磷酸铝、王浆酸、椰油胺、赖氨酸、增塑剂、浸膏粉、乙氧基
- 主营：碳化硅修补剂、金属修补剂、钢质修补剂、铁质修补剂、铝质修补剂、铜质修补剂、轴承位修补剂、轴磨损修补剂、高温胶水、高温修补剂、皮带胶、快速橡胶修补剂、金属导电胶水、电泳导电修补剂、搪瓷修补剂、搪瓷反应釜修补剂、高温搪瓷釜修补剂、高温密封胶、铸钢修补剂、耐磨陶瓷颗粒胶、导轨修补剂、模具修补剂、高温环氧树脂胶水、PP胶水、PU胶水
- 主营：异丙醇、冰醋酸、化工原料、二氯甲苯、正庚烷、甲基环己烷、乙二醇、苯酚、江苏异丙醇、江苏化工原料、工业吡啶、工业苯酚、正丁醇、MIBK、无水乙醇、正己烷
- 主营：防冻液、冰醋酸、乙二醇、二氯甲苯、冰乙酸、纯吡啶、丙二醇、羟基苯、14丁二醇、3-丙三醇、四氢呋喃、环保乙腈、化工苯酚、1.4丁二醇、医用苯酚、工业苯酚、精制苯酚、价位四氢、乙腈工业、乙酸乙酯、吡啶化工、甲酸乙酯、吡啶工业、求购苯酚、高纯三氯、实验乙腈
- 主营：叔碳酸、十八醛、溶菌酶、邻二氯苄、海藻糖、癸二醇、氨基丙基、氢路噻嗪、邻苯二甲、乙基碳二、羟基癸酸、正十七烷、谷胱甘肽、烷二甲醇、松果体素、vc磷酸酯镁、2-甲基丁醛、朱栾倍半萜、丁烷四乙酸、表面活性剂、癸烷撑二醇、缩水甘油邻、10-羟基羊蜡酸、氢氯噻嗪杂质、盐酸邻菲罗啉、壳聚糖季铵盐
- 主营：十六烷基三甲基溴化铵、十二烷基甜菜咸、乳化剂、亚磷酸三丁酯、棕榈油、钛酸四丁酯、钛酸四乙酯
- 主营：四氢噻吩、乙硫醇、单氰胺、二甲基二硫醚、3-甲硫基丙醛、四氢吡咯、邻氯苯腈、噻吩、盐酸羟胺、硬脂酸锌、异丙胺、氯乙酸、氟硼酸
- 主营：聚苯胺、脯氨酸甲酯盐酸盐、苄基三甲基氯化铵
- 主营：无水乙醇、乙酸乙酯、磷酸、二氯甲烷、甲醇、乙二醇、异丙醇、二甲苯、各种化学试剂、化工原料
- 主营：杀菌剂、椰子油、印染剂、二氯甲苯厂家、阻燃剂、油酸锌、润湿剂、硫酸铯、催化剂、粘合剂、乳化剂、草酸锰、硫酸锂、石英砂、绝缘油、茶皂素、防腐剂、醋酸镁、锂电池、碘化锂、培养基、蒸馏水、硬脂酸、塑化剂、草酸钾、磷酸铁
- 主营：甘氨酸、滑石粉、三甘醇、二氯甲苯可用作溶剂、生桐油、水杨酸、葡聚糖、石英砂、薄荷脑、苯甲醇、平平加、丁酸钠、磷酸氢、扩散剂、漂白精、硬脂酸、消泡剂、蛋白胨、硫化锌、磷酸铁、黄糊精、硫酸钾、磷酸铝、磷铁粉、雷米邦、氧化铅
- 主营：优氯净、二萘酚、硫酸锌、二氯甲苯可用作溶剂、封口蜡、甘露醇、水杨酸、硫酸锰、防染盐、正辛烷、牛磺酸、白僵菌、冰醋酸、铵明矾、肉桂醇、碳酸镁、肉桂醛、磷酸铝、戊二醛、沸石粉、硫化钠、硫化钡、硫化钙、氯化锌、黄原胶、磺酸钙