Overview
Dextropropoxyphene is a synthetic opioid analgesic that was first introduced in the 1950s. It is chemically related to methadone and is primarily used for the treatment of mild to moderate pain. Due to its potential for abuse and addiction, it has been withdrawn from the market in several countries. Despite its decline in use, dextropropoxyphene remains a subject of interest in pharmaceutical research. It is often combined with other analgesics like acetaminophen to enhance its efficacy. The drug works by binding to opioid receptors in the brain, thereby altering the perception of pain.
Physical and Chemical Properties
Dextropropoxyphene is a white crystalline powder with a molecular weight of 339.47 g/mol. It has a melting point of 74-76°C and is soluble in organic solvents like ethanol and methanol, but only slightly soluble in water. The compound's chemical stability is influenced by storage conditions. It should be kept in a cool, dry place away from light and moisture to prevent degradation. Its opioid properties are derived from its ability to bind to specific receptors in the central nervous system, which is a key feature of its pharmacological activity.
Main Applications
Dextropropoxyphene is primarily used for pain management, particularly for mild to moderate pain. It is often formulated in combination with other analgesics like acetaminophen to improve its effectiveness. In some cases, it has been used as an antitussive, although this application is less common. The drug's use has declined significantly due to concerns about its safety profile, including the risk of addiction and respiratory depression. However, it remains available in certain regions under strict regulations.
Safety and Storage
Dextropropoxyphene is a controlled substance in many countries due to its potential for abuse and addiction. It can cause respiratory depression, especially when taken in high doses or combined with other depressants like alcohol. Proper storage is essential to maintain the drug's stability. It should be kept in a cool, dry place away from light and moisture. Handling should comply with safety guidelines to minimize exposure, and disposal should follow local regulations to prevent environmental contamination.
B2B Procurement Guide
When procuring dextropropoxyphene, it is crucial to ensure compliance with local and international regulations. The drug is a controlled substance in many jurisdictions, and its purchase requires appropriate licenses and documentation. Buyers should source the compound from licensed suppliers to guarantee quality and authenticity. The reference price range is approximately $50-$100 per gram for pharmaceutical grade. Due to its declining use, availability may be limited, and buyers should verify the supplier's credentials before making a purchase.
Related Manufacturers
- 主营：右羟丙哌嗪、莪术二酮、人参皂苷rc
- 主营：药品检测标准品、药物杂质标准品、对照品、中药对照药材、中药农残空白基质、分析标准品、仪器检测校准品、金属离子标准溶液、滴定溶液、食品检测标准物质、有机检测标准溶液、指示液、缓冲液、电导率溶液、PH标准溶液、熔点标准品、国家标准物质、比色液
- 主营：中药对照品、药物杂质标准品、中药农产空白基质、分析标准品、药典标准溶液、标准物质、标准品、对照品