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Deoxycholic Acid Intermediate

Updated: 2026-07-24

Overview

Deoxycholic acid intermediate is a crucial chemical in the synthesis of deoxycholic acid, a naturally occurring bile acid. It serves as a precursor in pharmaceutical manufacturing, particularly for drugs targeting metabolic and digestive disorders. The intermediate is typically produced through controlled chemical reactions, ensuring high purity and consistency for industrial use. Due to its role in producing deoxycholic acid, this intermediate is in demand across the pharmaceutical and biochemical industries. Its synthesis involves specific organic reactions, often requiring specialized equipment and expertise to maintain quality standards.

Physical and Chemical Properties

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Deoxycholic acid intermediate is generally a white to off-white powder or crystalline solid. It exhibits solubility in common organic solvents such as ethanol and methanol, though it is only slightly soluble in water. The compound is stable under recommended storage conditions but may degrade if exposed to excessive heat or moisture. Key properties include high purity and stability, making it suitable for further chemical processing. While specific molecular weight and formula may vary depending on the exact intermediate form, suppliers typically provide detailed specifications to ensure compatibility with end-use applications.

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Main Applications

The primary application of deoxycholic acid intermediate is in the pharmaceutical industry, where it serves as a precursor for deoxycholic acid. Deoxycholic acid itself is used in medications for dissolving gallstones and as an emulsifier in drug formulations. The intermediate is also employed in biochemical research for studying bile acid metabolism and related pathways. Additionally, this intermediate may find use in cosmetic and dermatological products, leveraging its properties to enhance formulation stability. Its versatility in synthesis makes it valuable for producing derivatives with tailored pharmacological effects.

Safety and Storage

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Handling deoxycholic acid intermediate requires adherence to safety protocols to minimize risks. Workers should use appropriate personal protective equipment (PPE), including gloves and safety goggles, to prevent skin contact or inhalation. The compound should be stored in a cool, dry environment, away from direct sunlight and moisture, to maintain its stability. In case of accidental exposure, rinse affected areas with plenty of water and seek medical advice if irritation persists. Proper disposal methods should follow local regulations to avoid environmental contamination. Suppliers often provide Material Safety Data Sheets (MSDS) for detailed safety information.

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B2B Procurement Guide

When procuring deoxycholic acid intermediate, B2B buyers should prioritize suppliers with a proven track record in chemical manufacturing. Key considerations include verifying certificates of analysis (COA) to ensure product purity and consistency. Compliance with Good Manufacturing Practices (GMP) is essential for pharmaceutical-grade intermediates. Buyers should also evaluate pricing, which typically ranges from $50 to $200 per kilogram, depending on purity and order volume. Establishing long-term relationships with reliable suppliers can help secure stable pricing and timely deliveries. Additionally, inquire about packaging options to ensure the product arrives in optimal condition.

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