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D-Ribose

Updated: 2026-07-17

Overview

D-Ribose is a simple sugar and a key component of RNA, ATP, and other vital biomolecules. It is naturally produced in the body and is crucial for cellular energy metabolism. As a supplement, D-Ribose is popular among athletes and individuals with certain medical conditions due to its role in enhancing energy production and recovery. In industrial settings, D-Ribose is synthesized through fermentation or chemical processes. It is widely used in pharmaceuticals for drug formulations and in the food industry as a sweetener and energy booster. Its importance in biochemistry and health makes it a valuable compound in both medical and commercial applications.

Physical and Chemical Properties

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D-Ribose is a white, crystalline powder with a sweet taste. It is highly soluble in water, making it easy to incorporate into liquid formulations. The compound is stable under normal storage conditions but should be protected from moisture to prevent clumping or degradation. Chemically, D-Ribose is a pentose sugar with the molecular formula C5H10O5. It has a melting point of 88-92 °C and is optically active, meaning it can rotate plane-polarized light. These properties make it distinct from other sugars and contribute to its specific biological functions.

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Main Applications

D-Ribose is primarily used in the pharmaceutical industry for formulating drugs that support cardiovascular health and muscle recovery. It is also a common ingredient in sports nutrition products, such as energy bars and drinks, due to its ability to replenish ATP levels quickly. In the food industry, D-Ribose serves as a natural sweetener and flavor enhancer. Additionally, it is used in research laboratories for studying metabolic pathways and enzyme functions. Its versatility and safety profile make it a preferred choice in multiple sectors.

Safety and Storage

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D-Ribose is generally recognized as safe (GRAS) by regulatory authorities. However, excessive consumption may lead to mild gastrointestinal issues such as bloating or diarrhea. It is advisable to adhere to recommended dosages, especially in supplement form. For storage, D-Ribose should be kept in a cool, dry place, away from direct sunlight and moisture. Properly sealed containers are essential to maintain its stability and shelf life. Bulk procurement should ensure packaging integrity to prevent contamination or degradation during transit.

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B2B Procurement Guide

When procuring D-Ribose in bulk, buyers should prioritize suppliers with certifications such as USP or FCC, which guarantee purity and quality. Testing for contaminants and verifying the molecular weight (150.13 g/mol) are critical steps in quality assurance. Price negotiations should consider factors like order volume, purity levels (≥98%), and packaging requirements. Logistics planning should account for the compound's stability, ensuring timely delivery to prevent exposure to adverse conditions. Establishing long-term partnerships with reliable suppliers can ensure consistent quality and competitive pricing.

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