Overview
D-alpha-Tocopheryl Acetate is the esterified form of natural vitamin E (D-alpha-tocopherol), offering enhanced stability while retaining biological activity. It's synthesized through acetylation of D-alpha-tocopherol, creating a compound resistant to oxidation. As the most bioavailable form of vitamin E, it's preferred in formulations requiring long shelf life. The compound plays critical roles in human nutrition as a chain-breaking antioxidant and is essential for neurological functions. Its synthetic production ensures consistent quality for industrial applications, distinguishing it from mixed tocopherol products.
Physical and Chemical Properties
This vitamin E derivative presents as a viscous liquid at room temperature or crystallizes when pure. Its molecular structure contains a chromanol ring and phytyl side chain, with the acetate group at the C-6 position providing oxidative protection. The substance shows remarkable thermal stability below 200°C but gradually decomposes at higher temperatures. Unlike unesterified tocopherols, the acetate form demonstrates negligible antioxidant activity until hydrolyzed in the body. This property makes it ideal for formulations where premature oxidation must be prevented. The compound's lipophilic nature dictates its solubility profile, readily dissolving in oils and organic solvents.
Main Applications
In pharmaceuticals, D-alpha-Tocopheryl Acetate serves as an active ingredient in vitamin E supplements and parenteral nutrition formulations. Its stability allows incorporation into multivitamin tablets without significant degradation during processing or storage. The cosmetic industry values it for skin-conditioning properties in creams and anti-aging products. Food manufacturers utilize it as a nutrient fortificant in oils, cereals, and dairy alternatives. Compared to synthetic DL-alpha forms, the D-isomer shows approximately 36% higher biological activity. Industrial applications extend to animal feed additives and as a stabilizer in polymer production.
Safety and Storage
Regulatory agencies including FDA and EFSA classify this compound as safe for intended uses. Occupational exposure limits haven't been established due to low toxicity, though standard PPE (gloves, goggles) is recommended when handling concentrated forms. No significant ecological hazards have been identified. Proper storage requires amber glass or food-grade plastic containers with nitrogen blanketing to prevent oxidation. Under recommended conditions, the material maintains stability for 3-5 years. Bulk storage tanks should feature temperature control to prevent solidification in cold environments.
B2B Procurement Guide
Industrial buyers should prioritize suppliers with pharmaceutical-grade manufacturing capabilities (USP/EP compliance). Key specifications to verify include optical rotation (+24° to +26°), peroxide value (<10 mEq/kg), and heavy metal content (<10 ppm). Batch certificates should confirm absence of solvent residues. For international shipments, consider climate-controlled logistics to prevent thermal degradation. Many manufacturers offer customized formulations (oil solutions, beadlets) for specific applications. Minimum order quantities typically range from 25kg for premium grades to metric ton quantities for standard industrial material.
Related Manufacturers
- 主营：三硫代碳酸钠、红色素-16、聚乙烯亚胺、生育酚醋酸酯、三乙二醇二异辛酸酯、巯基苯并噻唑钠、L-丙交酯、乙交酯、石油酯-T50、多元醇苯甲酸酯、热压敏染料、光稳定剂、高分子降解材料
- 主营：木质醛、酮锌吡、褪黑素、生育酚、甘油酯、粘蛋白、薄荷脑、苯氨基、苹果酸、三羟基、皮粉五、甲基蓝、生根粉、动力精、薄荷酮、二羟基、3α羟基、萘酰胺、胶粘剂、磷酸三、嗪二酮、氨酸钾、嘧啶酮、氨酸镁、407环氧、酸cas号
- 主营：生育酚、网站建设、企业官网设计、网站搭建
- 主营：生育酚、异VC钠、中盐软水盐
- 主营：生物原料、植物提取物
- 主营：生育酚醋酸酯粉、水解蚕丝蛋白、吡咯烷酮羧酸镁、二氨基嘧啶氧化物
- 主营：甘氨酸、溴化物、戊酸鈉、生育酚醋酸酯、蒽甲酸、联吡啶、紫苏葶、锂电池、牛磺酸、褪黑素、磷酸铟、新癸酸、赖氨酸、溴化鏻、乙氧基、藏花醛、豆甾醇、羟乙基、维素酶、庚二酸、呋虫胺、丹参素、萘甲醛、槐豆胶、黄柏酮、元明粉