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D-Allulose

Updated: 2026-08-02

Overview

D-Allulose, also known as D-Psicose, is a rare monosaccharide sugar with a similar taste profile to sucrose but significantly lower caloric content (approximately 0.4 kcal/g). It occurs naturally in small quantities in wheat, figs, and raisins. Due to its unique metabolic properties—absorbed but not metabolized by the body—it has gained traction as a sugar substitute in the food and beverage industry. Recognized as GRAS by the U.S. FDA in 2011, D-Allulose is increasingly used in products targeting reduced-calorie and diabetic-friendly formulations. Its functional properties, such as moisture retention and browning effects, make it versatile for baked goods, dairy, and confectionery applications.

Physical and Chemical Properties

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D-Allulose is a white, odorless crystalline powder with a clean sweet taste, about 70% as sweet as sucrose. Its molecular structure (C6H12O6) is an epimer of fructose, differing only in the configuration of the C-3 hydroxyl group. This minor structural change results in its low caloric impact. The sugar exhibits high solubility in water (approximately 290 g/100 mL at 20°C) and is stable under typical food processing conditions, including moderate heat (up to 120°C). Unlike artificial sweeteners, it does not leave a bitter aftertaste, making it preferable for natural-label products.

Main Applications

In the food industry, D-Allulose is primarily used as a sucrose substitute in low-calorie beverages, ice cream, yogurt, and sugar-free confectionery. Its ability to mimic sucrose’s texture and mouthfeel—without spiking blood glucose—makes it ideal for diabetic-friendly products. Pharmaceutical applications include its use as an excipient in chewable tablets and syrups, leveraging its sweetness and non-cariogenic properties. Emerging research also explores its potential in weight management and metabolic health supplements due to its minimal glycemic impact.

Safety and Storage

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D-Allulose is classified as GRAS and is safe for consumption within typical dietary amounts. Excessive intake (≥0.9 g/kg body weight) may cause transient bloating or diarrhea due to incomplete absorption in the small intestine. For storage, the powder should be kept in airtight containers at room temperature (20-25°C) with relative humidity below 65%. Prolonged exposure to moisture can lead to clumping, though this does not affect its chemical stability.

B2B Procurement Guide

When sourcing food-grade D-Allulose, prioritize suppliers with ISO 22000 or FSSC 22000 certifications to ensure compliance with food safety standards. Key specifications to verify include purity (≥98%), residual solvent levels, and microbial counts. Bulk pricing typically ranges from $20-50/kg, depending on order volume and purity. For international shipments, confirm that the supplier provides documentation aligning with regional regulations (e.g., FDA GRAS, EU Novel Food approval). Sample testing for sensory and functional properties is recommended before large-scale procurement.

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