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Cystine

Updated: 2026-08-06

Overview

L-Cystine is a sulfur-containing amino acid that plays a crucial role in protein structure and antioxidant defense mechanisms. It is a dimer of cysteine, connected by a disulfide bond, and is commonly used in various industrial applications. L-Cystine is naturally found in keratin-rich tissues such as hair, nails, and skin, making it valuable in cosmetic and pharmaceutical formulations. In industrial settings, L-Cystine is synthesized or extracted from natural sources for use in dietary supplements, food additives, and therapeutic products. Its ability to form disulfide bonds makes it essential for stabilizing proteins and peptides, which is why it is widely used in biotechnology and medicine.

Physical and Chemical Properties

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L-Cystine appears as a white crystalline powder with a molecular weight of 240.30 g/mol. It has a density of 1.677 g/cm³ and decomposes at temperatures between 260-261°C. The compound is slightly soluble in water but insoluble in most organic solvents, which influences its handling and formulation in industrial processes. Key chemical properties include its role in forming disulfide bonds, which are critical for the structural integrity of proteins. L-Cystine also exhibits antioxidant properties, making it useful in formulations aimed at reducing oxidative stress. These properties are leveraged in pharmaceuticals, cosmetics, and food products to enhance stability and efficacy.

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Main Applications

L-Cystine is extensively used in the pharmaceutical industry for manufacturing drugs that treat conditions like liver disease, respiratory disorders, and skin ailments. Its role in protein synthesis and antioxidant activity makes it a valuable ingredient in therapeutic formulations. In the food industry, L-Cystine serves as a dough conditioner and flavor enhancer, particularly in baked goods. It is also added to animal feed to promote growth and improve fur quality. Additionally, the cosmetic industry utilizes L-Cystine in hair and skin care products due to its ability to strengthen keratin structures and repair damaged tissues.

Safety and Storage

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L-Cystine is generally considered safe for use in industrial and consumer products, but proper handling is essential to avoid potential hazards. Workers should use personal protective equipment (PPE) such as gloves and masks to prevent inhalation or skin contact. Storage conditions are critical to maintaining the stability of L-Cystine. It should be kept in a cool, dry place away from direct sunlight and moisture to prevent degradation. Bulk quantities are typically stored in sealed containers with desiccants to absorb any ambient humidity, ensuring long-term usability.

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B2B Procurement Guide

When procuring L-Cystine, industrial buyers should prioritize suppliers with certified quality control measures. Key factors to consider include purity levels (typically 98.5%-99.5%), packaging integrity, and compliance with regulatory standards such as USP or EP. Price negotiations should account for order volume, with discounts commonly available for bulk purchases. Buyers are advised to request samples for lab testing before committing to large orders. Additionally, verifying the supplier’s ability to provide consistent quality and timely delivery is crucial for maintaining smooth production processes.

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