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Cyclopentanolide

Updated: 2026-08-30

Overview

Cyclopentanol, also known as hydroxycyclopentane, is a cyclic alcohol with the molecular formula C5H10O. It is a colorless liquid with a characteristic camphor-like odor. This compound is primarily used in organic synthesis and as an intermediate in pharmaceutical manufacturing. Its unique chemical structure makes it valuable for producing various derivatives. Cyclopentanol is synthesized through the hydrogenation of cyclopentanone or via other catalytic processes. It is commercially available in varying purities, with industrial-grade and pharmaceutical-grade being the most common. Due to its versatile applications, it is a significant chemical in several industries.

Physical and Chemical Properties

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Cyclopentanol exhibits typical alcohol properties, including solubility in water and organic solvents like ethanol and ether. It has a density of 0.948 g/cm³ at 20°C and boils at 140-141°C. The melting point is -19°C, making it a liquid at room temperature. The compound is flammable and volatile, requiring careful handling to avoid ignition. Its camphor-like odor is distinctive but can be irritating at high concentrations. Cyclopentanol's reactivity includes participation in esterification, oxidation, and substitution reactions, making it useful in synthetic chemistry.

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Main Applications

Cyclopentanol serves as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and fragrances. It is used to produce cyclopentyl derivatives, which are components in drugs targeting central nervous system disorders. In the fragrance industry, it contributes to camphor-like scents. Additionally, cyclopentanol acts as a solvent for resins, oils, and other organic compounds. Its role in organic synthesis includes being a precursor for cyclopentene and other cyclic compounds. Industrial applications also extend to lubricant additives and plasticizers.

Safety and Storage

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Cyclopentanol is a flammable liquid, necessitating storage in cool, dry, well-ventilated areas away from heat and open flames. Containers should be tightly sealed to prevent evaporation and moisture absorption. Proper grounding is required to avoid static discharge. Personal protective equipment (PPE) such as gloves, goggles, and respirators should be used when handling. In case of spills, absorb with inert material and dispose of according to local regulations. Avoid skin contact and inhalation to prevent irritation or systemic effects.

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B2B Procurement Guide

When procuring cyclopentanol, prioritize suppliers with certifications like ISO or GMP, ensuring product quality and consistency. Request detailed specifications, including purity levels (e.g., ≥98%) and impurity profiles. Bulk purchases may offer cost savings, but verify storage capabilities. Logistics should accommodate flammable liquid regulations, including proper labeling and transportation. Establish long-term contracts with reliable suppliers to secure stable pricing and availability. Always check for compliance with regional chemical safety standards.

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