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Cyclooctanone

Updated: 2026-07-15

Overview

Cyclooctanone is an organic compound belonging to the class of cyclic ketones. It is characterized by an eight-membered carbon ring with a carbonyl group. This compound is primarily utilized in industrial and laboratory settings for its reactivity in organic synthesis. Cyclooctanone is synthesized through various methods, including the oxidation of cyclooctanol or the catalytic cyclization of suitable precursors. Its unique structure makes it valuable in the production of complex organic molecules.

Physical and Chemical Properties

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Cyclooctanone is a colorless to pale yellow liquid with a distinct odor. It has a molecular weight of 126.20 g/mol and a density of 0.91 g/cm³ at 25°C. The compound boils at 195-197°C and is soluble in common organic solvents like ethanol and ether, though its solubility in water is limited. As a cyclic ketone, cyclooctanone exhibits typical ketone reactivity, participating in reactions such as nucleophilic addition and condensation. Its stability under normal conditions makes it suitable for various chemical processes.

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Main Applications

Cyclooctanone is widely used in organic synthesis, particularly in the production of pharmaceuticals and fragrances. It serves as a key intermediate in the synthesis of complex organic molecules, including steroids and other cyclic compounds. In the fragrance industry, cyclooctanone contributes to the creation of musky and woody scents. Its reactivity and structural properties also make it valuable in polymer chemistry and materials science.

Safety and Storage

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Cyclooctanone is a flammable liquid and should be handled with care. It may cause irritation to the skin, eyes, and respiratory system upon exposure. Proper personal protective equipment, such as gloves and goggles, is recommended when working with this compound. Storage should be in a cool, dry, well-ventilated area away from heat sources and open flames. Containers should be tightly sealed to prevent evaporation and contamination.

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B2B Procurement Guide

When procuring cyclooctanone, it is essential to verify the purity and quality of the product. Reputable suppliers should provide certificates of analysis (CoA) and material safety data sheets (MSDS). Bulk purchasing may offer cost advantages, but storage capacity and shelf life should be considered. Procurement professionals should also evaluate supplier reliability, delivery timelines, and compliance with industry standards. Custom synthesis options may be available for specific requirements.

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