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Cyclohexylurea

Updated: 2026-08-03

Overview

Cyclohexylurea is an organic compound with the molecular formula C7H14N2O. It is a white crystalline powder that is widely used in pharmaceutical intermediates and organic synthesis. The compound is known for its stability and solubility in both water and organic solvents. Cyclohexylurea is synthesized through the reaction of cyclohexylamine with urea or its derivatives. Its applications span across various industries, particularly in the development of pharmaceuticals where it serves as a key intermediate.

Physical and Chemical Properties

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Cyclohexylurea is characterized by its white crystalline appearance and a melting point ranging between 160-165°C. It is soluble in water and common organic solvents such as ethanol and methanol. The compound is stable under normal conditions and does not exhibit hygroscopic properties. The molecular weight of cyclohexylurea is 142.20 g/mol. Its stability makes it suitable for long-term storage when kept in appropriate conditions. The compound's solubility profile allows it to be easily incorporated into various chemical processes.

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Main Applications

Cyclohexylurea is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also employed in organic synthesis for the preparation of other urea derivatives. Its role in these processes is crucial due to its reactivity and stability. Beyond pharmaceuticals, cyclohexylurea finds applications in agrochemicals and specialty chemicals. Its versatility makes it a valuable compound in research and industrial settings, contributing to the development of new chemical entities.

Safety and Storage

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When handling cyclohexylurea, it is essential to use appropriate personal protective equipment (PPE) such as gloves and goggles. The compound should be stored in a cool, dry place away from moisture and direct sunlight to maintain its stability. In case of skin contact, wash immediately with plenty of water. Avoid inhalation of dust and ensure adequate ventilation in the working area. Proper storage and handling minimize risks associated with chemical exposure.

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B2B Procurement Guide

When procuring cyclohexylurea, B2B buyers should prioritize suppliers with verified credentials and a track record of delivering high-quality chemicals. Requesting a Certificate of Analysis (COA) is crucial to confirm the compound's purity and compliance with specifications. Price ranges for cyclohexylurea typically fall between $50-$100 per kilogram, depending on purity and order volume. Bulk purchases may offer cost advantages. Ensure that the supplier adheres to safe packaging and transportation practices to prevent contamination or degradation.

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