Overview
Cyclohexanecarboxylic acid is a cycloaliphatic carboxylic acid derived from cyclohexane. It serves as a versatile intermediate in organic chemistry due to its stable cyclohexane ring and reactive carboxyl group. The compound is synthesized through oxidation or hydrogenation of benzoic acid derivatives. Industrially, it is produced in bulk for applications ranging from pharmaceutical precursors to fragrance additives. Its compatibility with various solvents and moderate acidity makes it suitable for diverse synthetic pathways.
Physical and Chemical Properties
The acid exists as a colorless liquid at room temperature with a characteristic faint odor. It has a density of 1.048 g/cm³ and melts at 29-31°C, boiling at 232-234°C. Its solubility profile favors organic solvents like ethanol and ether, though it exhibits limited solubility in water. Chemically, it behaves as a typical carboxylic acid, forming salts, esters, and amides. Its cyclohexane backbone contributes to steric stability, reducing reactivity compared to aromatic analogs. The pKa is approximately 4.9, indicating moderate acidity.
Main Applications
In pharmaceuticals, cyclohexanecarboxylic acid is a key intermediate for anticonvulsants and anti-inflammatory drugs. Its ester derivatives are used in perfumery for woody or herbal notes. The agrochemical industry employs it in pesticide synthesis. Additionally, it acts as a corrosion inhibitor in metalworking fluids and a pH adjuster in specialty chemicals. Research labs utilize it for chiral resolution due to its stereochemical properties.
Safety and Storage
The compound is mildly corrosive and requires handling with nitrile gloves and eye protection. Inhalation of vapors may irritate respiratory tracts; use fume hoods for large-scale operations. Storage should be in tightly sealed containers away from oxidizers. In case of spills, neutralize with sodium bicarbonate and absorb with inert materials. Dispose of waste according to local regulations for carboxylic acids. Shelf life exceeds two years when stored below 30°C.
B2B Procurement Guide
Industrial buyers should prioritize suppliers offering GC/MS purity certificates (≥98%) and consistent batch testing. Bulk shipments (drums or IBCs) typically reduce costs by 15-20% compared to retail packaging. Evaluate supplier compliance with ISO 9001 or similar standards. Spot prices fluctuate with benzene feedstock costs; long-term contracts may stabilize pricing. Request safety data sheets (SDS) and technical bulletins for regulatory compliance.
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