Overview
Cyazofamid is a systemic fungicide belonging to the imidazole class, developed to combat oomycete pathogens such as Phytophthora and Pythium species. It is widely used in agriculture due to its targeted action and low environmental impact. The compound works by inhibiting mitochondrial respiration in pathogens, making it a critical tool for crop protection. First introduced in the early 2000s, cyazofamid has gained regulatory approval in multiple countries, including the U.S., EU, and Japan. Its efficacy against late blight in potatoes and downy mildew in grapes has made it a preferred choice for integrated pest management (IPM) programs.
Physical and Chemical Properties
Cyazofamid is characterized by its white crystalline appearance and moderate solubility in organic solvents like acetone and methanol. Its molecular structure includes a sulfonamide group, which contributes to its systemic activity in plants. The compound is stable under normal storage conditions but may degrade under prolonged exposure to UV light or high temperatures. With a melting point of 152-154°C, cyazofamid exhibits low volatility, reducing the risk of airborne exposure during handling. Its solubility in water is limited (approximately 20 mg/L at 20°C), which ensures minimal leaching into groundwater when applied as directed.
Main Applications
Cyazofamid is primarily used to control oomycete diseases in high-value crops, including potatoes, grapes, tomatoes, and cucurbits. It is applied as a foliar spray or soil treatment, depending on the target pathogen. For potatoes, it effectively suppresses late blight (Phytophthora infestans), while in vineyards, it controls downy mildew (Plasmopara viticola). The fungicide is often integrated into resistance management programs due to its unique mode of action. It is compatible with other agrochemicals but should be rotated with non-imidazole fungicides to delay pathogen resistance. Its use is regulated in many regions, with maximum residue limits (MRLs) established for food safety.
Safety and Storage
Cyazofamid is classified as moderately hazardous (WHO Class II) and requires careful handling. Personal protective equipment (PPE), including gloves, goggles, and respirators, is recommended during application. Avoid contact with skin or eyes, and do not ingest or inhale the powder. Store the compound in its original container, tightly sealed, and away from food or feed. Ideal storage conditions include temperatures below 30°C and relative humidity under 60%. Dispose of unused material according to local hazardous waste regulations. Spills should be contained with inert absorbents and cleaned promptly.
B2B Procurement Guide
When procuring cyazofamid, prioritize suppliers with ISO or GLP certification to ensure quality consistency. Key specifications to verify include purity (≥95%), CAS number (120116-88-3), and absence of heavy metal contaminants. Request certificates of analysis (CoA) and third-party lab reports for each batch. Bulk purchases (e.g., 25 kg drums) typically offer cost savings, but ensure proper storage capacity. For international shipments, confirm compliance with destination-country regulations, such as EPA (U.S.) or EC (EU) approvals. Lead times may vary; plan procurement ahead of seasonal demand peaks in agriculture.
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