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Coumatetralyl

Updated: 2026-07-15

Overview

Coumatetralyl, commonly known as 不穿孔复鼠灵 in Chinese, is a second-generation anticoagulant rodenticide. It is widely used for controlling rodent populations in agricultural, industrial, and residential settings. Unlike first-generation anticoagulants, coumatetralyl is more potent and requires fewer doses to be effective. Developed as a safer alternative to acute toxins, coumatetralyl works by inhibiting vitamin K epoxide reductase, leading to fatal hemorrhaging in rodents. Its slow-acting nature reduces the risk of bait shyness, making it a preferred choice for long-term pest management.

Physical and Chemical Properties

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Coumatetralyl is a yellowish crystalline powder with a molecular weight of 292.33 g/mol. It has a melting point range of 172-176°C and is slightly soluble in water but dissolves well in organic solvents like acetone and ethanol. The compound is stable under normal storage conditions but degrades when exposed to strong acids, bases, or UV light. Its anticoagulant properties are due to its ability to disrupt the blood clotting cascade, specifically by targeting vitamin K-dependent clotting factors.

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Main Applications

Coumatetralyl is primarily used in rodent control programs for agriculture, food storage facilities, and urban environments. It is formulated into baits, pellets, or powders to attract and eliminate rodents like rats and mice. In addition to its use in pest control, coumatetralyl is sometimes employed in research to study anticoagulant mechanisms. However, its application is strictly regulated due to its high toxicity to non-target species, including pets and wildlife.

Safety and Storage

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Due to its high toxicity, coumatetralyl must be handled with extreme care. Personal protective equipment (PPE), including gloves and masks, should be worn during application. Accidental ingestion or inhalation can lead to severe health effects, including internal bleeding. Storage should be in a cool, dry place, away from food and feed. Containers must be tightly sealed to prevent contamination. Disposal must comply with local hazardous waste regulations to minimize environmental impact.

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B2B Procurement Guide

When procuring coumatetralyl, B2B buyers should prioritize suppliers with proven track records in chemical distribution. Verify certifications such as ISO or GMP to ensure product quality and safety. Prices typically range from $50 to $100 per kg, depending on purity and order volume. Buyers should also confirm that the product meets local regulatory requirements for rodenticide use. Bulk purchases may qualify for discounts, but storage capacity and shelf life should be considered.

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