Overview
Coumaroyl, or 4-coumaroyl, is a functional group derived from coumaric acid, a hydroxycinnamic acid. It is a key intermediate in the biosynthesis of lignin and flavonoids in plants. The compound is notable for its aromatic properties and is widely utilized in industries such as pharmaceuticals, cosmetics, and food additives. Its derivatives, such as coumaroyl-CoA, play critical roles in metabolic pathways. The versatility of coumaroyl makes it a valuable component in synthetic chemistry and natural product extraction. It is often sourced from plants like clover, alfalfa, and certain fruits.
Physical and Chemical Properties
Coumaroyl appears as a pale yellow to white crystalline powder with a distinct aromatic odor. It has a molecular weight of 147.15 g/mol and a melting point around 210-215°C. The compound is soluble in organic solvents like ethanol and methanol but only slightly soluble in water. Key chemical properties include its ability to absorb UV light, making it useful in sunscreens and coatings. It also exhibits antioxidant activity, which is leveraged in preservatives and health supplements. The stability of coumaroyl under normal storage conditions makes it suitable for long-term use in formulations.
Main Applications
In the pharmaceutical industry, coumaroyl is used as an intermediate in the synthesis of anticoagulants, antimicrobials, and anti-inflammatory drugs. Its derivatives are also explored for potential anticancer properties. The flavor and fragrance industry values coumaroyl for its sweet, hay-like aroma, often incorporated into perfumes and food flavorings. Additionally, its UV-absorbing properties are utilized in cosmetics and plastics to enhance product durability against sunlight degradation.
Safety and Storage
Coumaroyl should be handled with care, as it may cause skin and eye irritation. Proper personal protective equipment (PPE), such as gloves and goggles, is recommended during handling. In case of contact, rinse immediately with water. Storage requires a cool, dry environment away from direct light and moisture to prevent degradation. Sealed containers are ideal to maintain purity and extend shelf life. Bulk quantities should be stored in compliance with local chemical storage regulations.
B2B Procurement Guide
When procuring coumaroyl, prioritize suppliers with certifications like ISO or GMP to ensure quality and consistency. Request detailed specifications, including purity levels (typically 95-99%) and CAS number verification. Pricing varies based on purity and order volume, with bulk purchases often discounted. Consider logistics, such as shipping conditions (e.g., temperature control for sensitive batches). Sample testing before large-scale orders is advisable to confirm suitability for intended applications.
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