Overview
Industrial grade copovidone is a synthetic copolymer composed of vinylpyrrolidone (VP) and vinyl acetate (VA) monomers. It combines the adhesive properties of polyvinylpyrrolidone (PVP) with the flexibility imparted by the VA component. This polymer is produced through free-radical polymerization and is available in various molecular weights (K-values) to suit different industrial requirements. As a non-ionic polymer, copovidone exhibits excellent solubility in both water and organic solvents, making it versatile for diverse applications. The industrial grade differs from pharmaceutical grades primarily in residual monomer content and purity specifications, though both share similar fundamental properties.
Physical and Chemical Properties
Industrial copovidone appears as a free-flowing white powder with a characteristic slight odor. Its glass transition temperature typically ranges between 100-110°C, varying with the VP/VA ratio. The polymer's solubility profile allows it to form clear, viscous solutions in water (up to 50% w/v) and alcohol mixtures. Key chemical properties include hygroscopicity (moisture absorption up to 30% at high humidity) and pH stability (effective between 3-10). The K-value, which indicates molecular weight, ranges from 25 to 32 for most industrial applications. Unlike pure PVP, copovidone offers improved flexibility in dried films due to the VA component's plasticizing effect.
Main Applications
In the pharmaceutical industry, industrial grade copovidone serves as a binder in tablet formulations and a film-coating agent for controlled-release drugs. Its adhesive properties make it valuable in glue stick formulations and specialty adhesives where water solubility is required. Industrial applications include use as a thickening agent in inks and coatings, where it improves rheological properties. The textile industry employs it as a sizing agent, while agrochemical formulations utilize it for pellet cohesion. Recent developments explore its use in 3D printing as a soluble support material due to its clean dissolution characteristics.
Safety and Storage
Copovidone is generally recognized as safe for industrial handling, with no significant toxicity at normal exposure levels. However, powder forms may cause respiratory irritation upon inhalation, requiring NIOSH-approved dust masks during bulk handling. Eye contact may lead to temporary discomfort, necessitating safety goggles in powder processing areas. Proper storage requires moisture-proof containers in cool (15-25°C), dry conditions. Bulk bags should be placed on pallets to prevent floor moisture absorption. Shelf life typically exceeds 3 years when stored correctly, though clumping may occur in humid environments without affecting chemical stability.
B2B Procurement Guide
When sourcing industrial copovidone, buyers should specify the required K-value (molecular weight range) as it directly affects solution viscosity and film strength. For critical applications, request certificates analyzing residual monomer content (should be <0.1% for most uses) and heavy metal impurities. Consider ordering in moisture-resistant packaging (e.g., aluminum-lined bags) for humid climates. Price breaks typically occur at order quantities above 500kg. Reputable suppliers should provide technical data sheets with dissolution rate testing and compatibility studies for your specific application. For pharmaceutical-adjacent uses, inquire about GMP-compliant production facilities even for industrial grade material.
Related Manufacturers
- 主营：定妆剂、成膜剂、涂料分散剂、高纯度聚维酮、工业级聚维酮、化妆品级聚维酮、护发凝胶原料、化妆品护发原料、聚乙烯吡咯烷酮、易溶水乙醇甲醇
- 主营：交联聚维酮、聚维酮K系列、共聚维酮、聚乙烯吡咯烷酮、N-乙烯基吡咯烷酮
- 主营：甘氨酸、水苏糖、阻燃剂、共聚维酮VA64、硫酸锌、硫酸锆、硫酸锂、硫酸锶、硫酸锰、铝酸锌、1680-21-3、牛磺酸、褪黑素、磷酸铁、丙酸铵、苏云金、碳酸镁、麝香酮、肉桂醛、磷酸铝、王浆酸、椰油胺、赖氨酸、增塑剂、浸膏粉、乙氧基
- 主营：合成树脂、固化剂、不饱和树脂、共聚维酮、环氧树脂、聚酯多元醇、酚醛树脂、医药中间体
- 主营：异辛醇、乳化剂、乙烯醚、共聚维酮、醚羧酸、脂肪醇、分散剂、染色助剂、聚乙二醇、异构醇醚、泊洛沙姆、椰油酰胺、基羟乙基、烷基糖苷、特辛基酚、聚氧乙烯、嵌段聚醚、单油酸酯、异构十三醇、丙烯磺酸钠、氢化蓖麻油、丙烯酰胺基、醇醚葡糖苷、低泡渗透剂、甲酯乙氧基、癸基葡糖苷
- 主营：阻燃剂、拉那白、牛儿酮、聚维酮S、海藻糖、热敏蓝、萘磺酸、氯菊酯、硫酸锌、催化剂、杨梅酯、檀香醚、聚醚胺、吸收剂、脂檀油、苍术素、羟钴胺、转移剂、溶剂绿、麝香酮、王浆酸、芬多精、纤维素、新戊酯、王冠醚、遮甜粉
- 主营：桐油、甘油、油酸、二甲基硅油、工业骨胶、二茂铁、间苯二酚、丙烯酸乳液、乙酸乙烯酯共聚乳液、丁苯胶乳、二甘醇、无水乙醇、乙二醇、异丙醇、正丁醇、乙酸乙酯、乙酸甲酯、乙酸丁酯、二氯甲烷、甲醇、二甲苯、三氯乙烯、丙二醇甲醚醋酸酯、二价酸酯
- 主营：硬脂酸镁、药用聚乙二醇、泊洛沙姆188、聚维酮k30、聚维酮k90、交联聚维酮、泊洛沙姆407、聚乙二醇—15羟基硬脂酸酯、巴斯夫进口蓖麻油聚烃氧酯EL35、巴斯夫聚氧乙烯氢化蓖麻油RH40、巴斯夫进口Soluplus、微晶纤维素、羧甲淀粉钠、低取代羟丙纤维素、羟丙纤维素、羟丙甲纤维素、乳糖、麦芽糊精、交联羧甲纤维素钠、海藻糖、甘羟铝、聚丙烯酸钠、卡波姆、亚什兰进口羟乙基纤维素
- 主营：有机原料、中间体、香精香料、催化剂、有机硅、表面活性剂
- 主营：全氟三丁胺、二苄叉山梨醇、六氟丙烯二聚体、共聚维酮、六氟环氧丙烷二聚体、异丙醇铝、纳米勃姆石、二异戊基硫醚、隐色结晶紫、邻菲罗啉
- 主营：防冻液、冰醋酸、乙二醇、共聚维酮、冰乙酸、纯吡啶、丙二醇、羟基苯、14丁二醇、3-丙三醇、四氢呋喃、环保乙腈、化工苯酚、1.4丁二醇、医用苯酚、工业苯酚、精制苯酚、价位四氢、乙腈工业、乙酸乙酯、吡啶化工、甲酸乙酯、吡啶工业、求购苯酚、高纯三氯、实验乙腈
- 主营：海藻糖、柠檬酸、黄原胶、共聚维酮、氯化钙、薄荷脑、泊洛沙姆、聚乙烯醇PVA、聚山梨酯、碳酸氢钠、注射蛋黄卵磷脂、注射大豆油、甘油、倍他环糊精、海藻酸钠、聚丙烯酸钠、酒石酸、丙二醇、聚乙二醇、HS15、聚氧乙烯40氢化蓖麻油、山嵛酸甘油酯、羟丙甲纤维素、羟苯甲酯钠
- 主营：聚乙烯亚胺、三甘醇二异辛酸酯3G8、三硫代碳酸钠40%、共聚维酮、TS-1钛硅分子筛、六氯环三磷腈、5-甲基靛红、烷基苯磺酸酯、苯基次磷酸钠、甲巯咪唑、吡啶硫酮锌、焦磷酸哌嗪、热敏材料、油酸甲酯、曲酸
- 主营：三硫代碳酸钠、红色素-16、聚乙烯亚胺、共聚维酮、三乙二醇二异辛酸酯、巯基苯并噻唑钠、L-丙交酯、乙交酯、石油酯-T50、多元醇苯甲酸酯、热压敏染料、光稳定剂、高分子降解材料
- 主营：共聚维酮、全氟三丁胺、木质素、吉氏色素
- 主营：药用级海藻糖、药用级蜂蜜、药用级甘油、进口亚什兰共聚维酮、药用级固体石蜡、药用级羟丙甲纤维素、药用级二甲基亚砜、药用级注射蔗糖、药用级羟苯乙酯、药用级硬脂酸