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Chloroquine Intermediate

Updated: 2026-08-03

Overview

Chloroquinoline intermediate is a vital chemical compound primarily used in the synthesis of pharmaceuticals and agrochemicals. It serves as a building block for more complex molecules, particularly in the production of antimalarial drugs and other therapeutic agents. Its significance lies in its reactivity and stability, making it a preferred choice for industrial synthesis. The compound is typically supplied as a crystalline powder, ensuring ease of handling and storage.

Physical and Chemical Properties

5-氯-8-羟基喹啉 CAS号130-16-5 有机合成 医药中间体中山市迪欣化工有限公司

Chloroquinoline intermediate exhibits a pale yellow to white crystalline appearance, with a molecular weight of 163.6 g/mol. It is soluble in common organic solvents like ethanol and acetone but has limited solubility in water. The compound has a melting point range of approximately 120-125°C, indicating its stability under moderate temperatures. Its molecular structure allows for versatile reactivity, making it suitable for various synthetic pathways.

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Main Applications

The primary use of chloroquinoline intermediate is in the pharmaceutical industry, where it acts as a precursor for antimalarial drugs and other medications. Its reactivity enables the synthesis of complex molecules with therapeutic properties. In agrochemicals, it is used to produce pesticides and herbicides, contributing to crop protection. The compound's versatility also extends to research and development, where it is employed in the creation of new chemical entities.

Safety and Storage

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Handling chloroquinoline intermediate requires adherence to safety protocols. Protective gloves and goggles are essential to prevent skin and eye contact. Inhalation should be avoided, and work should be conducted in a well-ventilated area. Storage conditions include keeping the compound in a cool, dry place, away from moisture and direct sunlight. Proper labeling and segregation from incompatible substances are also recommended to ensure safety.

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B2B Procurement Guide

When procuring chloroquinoline intermediate, buyers should prioritize purity and supplier reliability. Requesting a Certificate of Analysis (COA) and Safety Data Sheet (SDS) is crucial to verify quality and compliance. Price ranges vary depending on purity and supplier, typically falling between $50 and $200 per kg. Bulk purchases may offer cost advantages, but buyers should ensure consistent quality across batches. Establishing long-term relationships with reputable suppliers can enhance procurement efficiency.

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