Overview
Chlorogenic acid (CGA) is a polyphenolic compound naturally found in coffee beans, fruits, and some medicinal plants. It is a key bioactive ingredient known for its antioxidant and anti-inflammatory effects. Industrially, it is extracted from green coffee beans or other plant sources for use in pharmaceuticals, dietary supplements, and functional foods. Due to its ability to modulate glucose metabolism and reduce oxidative stress, CGA has gained attention in the health and wellness sector. It is also used in cosmetics for its skin-protective properties.
Physical and Chemical Properties
Chlorogenic acid is a light yellow to white crystalline powder with a molecular weight of 354.31 g/mol. It is soluble in water and polar organic solvents like ethanol and methanol. The compound has a melting point of 207-209°C and is stable under normal storage conditions. Its chemical structure includes a caffeic acid moiety linked to quinic acid, which contributes to its biological activities. CGA exhibits strong UV absorption, making it useful in analytical chemistry for quantification purposes.
Main Applications
In the pharmaceutical industry, chlorogenic acid is studied for its potential to manage diabetes, obesity, and cardiovascular diseases. It is a common ingredient in weight-loss supplements and energy-boosting formulations. The food industry uses CGA as a natural preservative and flavor enhancer, particularly in coffee-based products. In cosmetics, it is valued for its anti-aging and skin-brightening effects, often included in serums and creams.
Safety and Storage
Chlorogenic acid is generally recognized as safe (GRAS) for consumption in moderate amounts. However, excessive intake may lead to mild side effects like stomach upset. Proper storage in a cool, dry place away from direct sunlight is essential to maintain its stability. For industrial handling, use protective equipment to avoid inhalation or skin contact. Bulk storage should be in sealed containers to prevent moisture absorption and degradation.
B2B Procurement Guide
When sourcing chlorogenic acid, prioritize suppliers with certifications like ISO, GMP, or organic compliance. Request certificates of analysis (CoA) to verify purity (typically 95-98%) and contaminants like heavy metals or solvents. Consider the extraction method (e.g., water vs. ethanol extraction) as it affects the final product's suitability for specific applications. Price varies based on purity, sourcing (natural vs. synthetic), and order volume.