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Chicoric Acid

Updated: 2026-07-15

Overview

Chicoric acid is a naturally occurring phenolic compound primarily found in chicory (Cichorium intybus) and echinacea (Echinacea purpurea). It is known for its potent antioxidant properties and is widely studied for its potential health benefits. The compound is structurally characterized by two caffeic acid groups esterified to tartaric acid, contributing to its biological activity. In recent years, chicoric acid has gained attention in the pharmaceutical and nutraceutical industries due to its anti-inflammatory and immunomodulatory effects. It is also used in functional foods and cosmetics for its ability to neutralize free radicals and support skin health.

Physical and Chemical Properties

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Chicoric acid typically appears as a yellow to light brown powder with a molecular weight of 474.37 g/mol. It has a melting point around 200-205°C and is soluble in water, methanol, and ethanol, making it versatile for formulation in various products. The compound is stable under normal storage conditions but may degrade under prolonged exposure to light or high temperatures. Its chemical structure includes two caffeoyl groups, which are responsible for its strong antioxidant activity. The presence of tartaric acid enhances its solubility and bioavailability, making it suitable for oral and topical applications.

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Main Applications

Chicoric acid is primarily used in the pharmaceutical industry for its potential to modulate immune responses and reduce inflammation. It is a key ingredient in dietary supplements aimed at supporting immune health and combating oxidative stress. In the food industry, it is added to functional foods and beverages for its antioxidant benefits. The cosmetic industry also utilizes chicoric acid in skincare products for its ability to protect against UV-induced damage and promote collagen synthesis. Its natural origin and safety profile make it a preferred choice for clean-label and organic product formulations.

Safety and Storage

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Chicoric acid is generally considered safe for consumption and topical use in regulated doses. However, it is advisable to handle the compound with care, avoiding inhalation or direct contact with eyes. Proper storage in a cool, dry place away from light and moisture ensures its stability and longevity. For industrial applications, bulk quantities should be stored in airtight containers with desiccants to prevent moisture absorption. Suppliers should provide material safety data sheets (MSDS) and certificates of analysis (CoA) to ensure compliance with safety and quality standards.

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B2B Procurement Guide

When procuring chicoric acid, it is essential to verify the purity and quality of the product. Reputable suppliers should provide detailed specifications, including HPLC or GC-MS analysis reports. Buyers should also check for certifications such as ISO, GMP, or organic certifications, depending on the intended use. Price ranges vary based on purity and supplier, with high-purity grades (≥98%) commanding premium prices. Bulk purchases may offer cost savings, but buyers should ensure consistent quality across batches. Establishing long-term relationships with reliable suppliers can help secure stable pricing and supply chains.

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