Overview
Catalposide is an iridoid glycoside primarily extracted from plants of the Catalpa genus, such as Catalpa ovata. It has garnered attention for its bioactive properties, including anti-inflammatory and antioxidant effects. Researchers are exploring its potential in treating neurodegenerative diseases and metabolic disorders. In traditional medicine, catalposide has been used for its purported hepatoprotective and anti-diabetic benefits. Modern studies support these claims, highlighting its role in modulating oxidative stress and inflammation pathways.
Physical and Chemical Properties
Catalposide is a white crystalline powder with a molecular weight of 344.31 g/mol. It is highly soluble in polar solvents like water and methanol, facilitating its use in liquid formulations. The compound’s melting point ranges between 180-185°C, indicating moderate thermal stability. Its chemical structure includes a glucose moiety bound to an iridoid aglycone, which is responsible for its biological activity. Stability tests suggest it degrades under prolonged exposure to light or high temperatures, necessitating controlled storage conditions.
Main Applications
Catalposide is primarily used in pharmaceutical research for developing anti-inflammatory and neuroprotective drugs. Its ability to scavenge free radicals makes it a candidate for antioxidant therapies. Preclinical studies show promise in treating conditions like Alzheimer’s disease and liver fibrosis. Beyond medicine, it is incorporated into dietary supplements for its metabolic benefits. Some cosmetic formulations also leverage its antioxidant properties to combat skin aging. However, clinical applications remain under investigation.
Safety and Storage
Catalposide should be handled with standard laboratory precautions, including gloves and eye protection. While it is not classified as highly toxic, prolonged exposure may cause irritation. Proper ventilation is recommended when working with powdered forms. Storage requires protection from moisture and light. Ideal conditions are 2-8°C in airtight containers. Shelf life typically extends to two years under these conditions, though degradation should be monitored via HPLC.
B2B Procurement Guide
When procuring catalposide, prioritize suppliers with ISO certification and batch-specific COAs (Certificates of Analysis). Purity levels of ≥98% (HPLC) are standard for research-grade material. Bulk purchases (100g+) often reduce costs by 10-20%. Consider logistics: cold-chain shipping may be necessary for large orders. Negotiate lead times, as synthetic production can take 4-6 weeks. Some suppliers offer custom purity or formulation services for specialized applications.