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Calcium Gluconate

Updated: 2026-07-21

Overview

Calcium gluconate is a calcium salt derived from gluconic acid, known for its high bioavailability and safety profile. It is commonly used in the food, pharmaceutical, and agricultural industries due to its excellent solubility and non-toxic nature. As a food additive, it serves as a calcium fortifier in products like dairy, baked goods, and beverages. In pharmaceuticals, it is used to treat calcium deficiencies and as an antidote for magnesium poisoning. Its versatility makes it a valuable compound in B2B markets.

Physical and Chemical Properties

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Calcium gluconate appears as a white, odorless, crystalline powder or granules. It is highly soluble in water but only slightly soluble in alcohol, making it ideal for aqueous formulations. The compound decomposes at around 120°C without melting, which is typical for organic salts. Its molecular formula, C12H22CaO14, reflects its structure as a calcium salt of gluconic acid. The compound is stable under normal storage conditions but should be protected from moisture to prevent caking or degradation.

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Main Applications

In the food industry, calcium gluconate is widely used as a dietary supplement to fortify products with calcium, addressing deficiencies in populations. It is added to beverages, dairy products, and baked goods due to its neutral taste and solubility. In pharmaceuticals, it is administered intravenously to treat hypocalcemia or as an emergency treatment for hyperkalemia and magnesium toxicity. Agriculturally, it is used in animal feed to promote bone health and eggshell quality in poultry.

Safety and Storage

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Calcium gluconate is classified as generally safe for consumption and handling. However, dust inhalation should be avoided, and standard lab safety measures, such as gloves and goggles, are recommended during handling. Storage requires a cool, dry environment in tightly sealed containers to prevent moisture absorption. Bulk quantities should be stored on pallets away from walls to ensure proper ventilation and ease of inspection.

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B2B Procurement Guide

When procuring calcium gluconate, prioritize suppliers with certifications like USP, BP, or EP to ensure product purity. Packaging options range from 25 kg bags to tonnage quantities, with prices varying based on purity (typically 98-102%) and order volume. Key procurement considerations include verifying batch-specific Certificates of Analysis (CoA), lead times, and the supplier’s ability to provide technical support. For international shipments, confirm compliance with regional regulations (e.g., FDA, EFSA).

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