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Calcium Citrate

Updated: 2026-08-02

Overview

Calcium Citrate is a highly bioavailable calcium salt derived from citric acid. Unlike calcium carbonate, it does not require stomach acid for absorption, making it ideal for individuals with low stomach acid or those taking acid-reducing medications. It is commonly used in dietary supplements and fortified foods due to its neutral taste and excellent solubility. As a food additive, Calcium Citrate serves multiple functions, including as a calcium fortifier, pH regulator, and firming agent. Its chemical stability and compatibility with other ingredients make it a versatile choice for food and pharmaceutical manufacturers.

Physical and Chemical Properties

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Calcium Citrate presents as a fine white powder with no discernible odor. Its molecular structure allows for better solubility in water compared to other calcium salts, particularly in neutral or slightly acidic conditions. This property is crucial for its absorption in the human body. The compound decomposes rather than melts when heated, breaking down into calcium oxide and carbon dioxide. It is non-hygroscopic, meaning it doesn't readily absorb moisture from the air, which contributes to its excellent shelf stability in properly packaged forms.

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Main Applications

In the pharmaceutical industry, Calcium Citrate is a preferred form of calcium in supplements due to its superior absorption characteristics. It's particularly beneficial for postmenopausal women and elderly individuals who often have reduced stomach acid production. The food industry utilizes Calcium Citrate as a nutritional additive in products like orange juice, plant-based milks, and cereal products. It also functions as a leavening agent in baking powders and as a preservative in some processed foods. In industrial applications, it serves as a chelating agent in cleaning products.

Safety and Storage

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Calcium Citrate is generally recognized as safe by regulatory agencies worldwide when used as directed. However, powdered forms should be handled with care to avoid dust inhalation, which may cause respiratory irritation. Appropriate personal protective equipment is recommended during bulk handling. For storage, keep containers tightly sealed in a cool, dry environment. Although stable under normal conditions, prolonged exposure to high humidity may cause caking. Bulk quantities should be stored on pallets away from walls to ensure proper air circulation and prevent moisture absorption.

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B2B Procurement Guide

When sourcing Calcium Citrate commercially, verify the product meets relevant pharmacopeia standards (USP, EP, or JP) for pharmaceutical applications or food-grade specifications (FCC) for food uses. Key quality parameters include purity (typically 98-101%), heavy metal content (lead <5 ppm), and microbial limits. Consider the particle size distribution if the application requires specific dissolution properties. For large-volume purchases, request certificates of analysis and consider third-party testing for critical applications. Transportation should be in moisture-proof packaging, preferably with desiccants for international shipments.

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