Overview
Boc-D-Glutamine is a derivative of D-glutamine, protected by a tert-butoxycarbonyl (Boc) group. This modification enhances its stability during peptide synthesis, preventing unwanted side reactions. The compound is widely used in pharmaceutical research and the production of bioactive peptides. Its chiral nature makes it valuable for creating enantiomerically pure compounds, which are critical in drug development. Boc-D-Glutamine is typically supplied as a white crystalline powder, ensuring ease of handling and precise measurement in laboratory settings.
Physical and Chemical Properties
Boc-D-Glutamine exhibits a molecular weight of 246.26 g/mol and a melting point range of 85-90°C. It is soluble in polar organic solvents like DMF and DMSO but has limited solubility in water. The Boc group provides protection for the amine functionality, making the compound resistant to acidic conditions. The crystalline form ensures consistent purity, which is essential for reproducible results in synthetic applications. Its stability under typical peptide synthesis conditions makes it a preferred choice for researchers and manufacturers alike.
Main Applications
Boc-D-Glutamine is primarily used in peptide synthesis, where it serves as a building block for creating complex peptides and proteins. Its protected form allows for selective deprotection, enabling precise control over the synthetic process. In pharmaceutical research, it is employed to develop peptides with therapeutic potential, such as antimicrobial or anticancer agents. Additionally, it finds use in biochemical studies to investigate enzyme-substrate interactions and metabolic pathways involving glutamine.
Safety and Storage
Proper handling of Boc-D-Glutamine requires the use of PPE, including gloves and goggles, to prevent skin and eye contact. Inhalation of dust should be avoided, and operations should be conducted in a well-ventilated area or fume hood. Storage conditions recommend keeping the compound at 2-8°C in a dry environment, protected from light. Improper storage can lead to degradation, reducing its efficacy in synthetic applications. Always refer to the material safety data sheet (MSDS) for detailed safety instructions.
B2B Procurement Guide
When procuring Boc-D-Glutamine, ensure the supplier provides a certificate of analysis (CoA) detailing purity, CAS number, and batch-specific data. Bulk purchases may offer cost advantages, but verify storage and shelf-life considerations. Reliable suppliers often offer technical support and custom synthesis services, which can be beneficial for specialized applications. Comparing prices and lead times across multiple vendors can help optimize procurement strategies.
Related Manufacturers
- 主营：中间体、尿囊素、肉豆蔻酸异丙酯、谷氨酰胺、烯丙基羟乙基醚、苄基三乙基氯化铵、马来酸、乙酰苯肼、椰油基三甲基氯化铵
- 主营：邻苯甲酰苯甲酸、偶联剂、硅烷偶联剂、6-萘二羧酸、kh-602、十八硫醇、碳酸铯、胆酸钠、脱氧胆酸钠、去氧胆酸钠、去氢胆酸、溴代丙二醛、茶籽油、聚钨酸钠、氰乙酸甲酯、沙棘籽油、乙酰氧基氮杂环丁酮、桔子油、亚麻油、柠檬桉醇、芳樟醇、二氟苯胺、萃取剂、乙酰氧基苯乙烯
- 主营：乙酰肼、甲氧基聚乙二醇丙烯酸酯、甲基丙烯酸叔丁氨基乙酯、2'-联吡啶、丙半胱氨酸
- 主营：杂环化合物、丙烯酸系列
- 主营：n-甲基吡咯烷酮、科研试剂
- 主营：正己醇、福淋酚、十二烷酸、2-乙基己醇、氨基甲醛、正十一烷、化学试剂、氧化苄基、月桂氮酮、丙烷二羧酸、辛癸混合酸、肌醇六磷酸分析
- 主营：谷氨酰胺、分析纯试剂、化学实验检测
- 主营：谷氨酰胺、分析纯试剂
- 主营：BocD谷氨酰胺、氨基丁酸、漆酶、维生素
- 主营：碘海醇、葡甲胺、氨甲环酸、谷氨酰胺、盐酸柔红霉素、甘油磷酸钠、海藻糖、葡乙胺、古龙酸、托吡酯、潮霉素B、替卡西林钠克拉维酸钾、星孢菌素、盐酸阿霉素、碘帕醇
- 主营：硫酸汞、硝酸汞、雷尼镍、谷氨酰胺生产厂家、二十烷、丁二酸、硫化银、正己醇、硫酸镉、铋酸钠、苯甲醇、硅酸钠、正辛酸、硫酸镁、磷钨酸、滑石粉、草酸锡、蓖麻油、椰子油、钒试剂、异辛醇
- 主营：对照品、标准品、当归酸酐、谷氨酰胺、佛手柑内酯、新当归内酯、补骨脂甲素、补骨脂乙素、羟基芍药苷、阿魏酸松柏酯、水合氧化前胡素、豆甾醇葡萄糖苷
- 主营：谷氨酰胺、白蜡树素、百两金素、半齿泽兰素
- 主营：对甲基苯丙酮、金属钙、氢化钙、1-氨基哌啶、1-萘甲酸、间苯三酚、氢化锂、五氧化二钒、偏钒酸铵、己二酸二钠、氢化锂铝、丁二酮肟、硫氰酸铅、乙醇钠
- 主营：大小化工试剂