Overview
Bis(cyclohexanone) oxalyldihydrazone, commonly referred to as Cuprizone, is a chemical compound primarily used as a chelating agent in analytical chemistry. It is particularly valued for its ability to form stable blue complexes with copper ions, making it a key reagent in spectrophotometric methods for copper detection. The compound is also used in neuroscience research due to its ability to induce demyelination in animal models, aiding the study of diseases like multiple sclerosis. Its high specificity and reactivity with copper make it indispensable in both industrial and laboratory settings.
Physical and Chemical Properties
Bis(cyclohexanone) oxalyldihydrazone is a white to off-white crystalline powder with a molecular weight of 278.35 g/mol. It decomposes at temperatures around 210-215°C and is soluble in organic solvents such as ethanol, methanol, and DMSO, though it has limited solubility in water. The compound’s ability to chelate metal ions, especially copper, is its most notable chemical property, forming intensely colored complexes that are easily detectable via spectrophotometry. This property is leveraged in analytical applications where precise metal quantification is required. Stability under normal storage conditions is good, but exposure to light, moisture, or high temperatures should be avoided to prevent degradation. The compound’s reactivity with metals is pH-dependent, with optimal complex formation occurring in slightly acidic to neutral conditions. These characteristics underscore its utility in controlled laboratory environments.
Main Applications
The primary application of bis(cyclohexanone) oxalyldihydrazone is in analytical chemistry, where it serves as a spectrophotometric reagent for copper determination. Its high selectivity for copper ions allows for accurate measurements even in the presence of other metals, making it valuable for environmental, industrial, and biological sample analysis. Additionally, the compound is used in biochemistry and neuroscience research, particularly in studies involving demyelination and remyelination processes. In industrial settings, it is employed in quality control laboratories for metal impurity testing in pharmaceuticals, food products, and water supplies. Its role in neuroscience research stems from its ability to induce reversible demyelination in animal models, providing insights into diseases like multiple sclerosis. These diverse applications highlight its versatility across scientific and industrial fields.
Safety and Storage
Bis(cyclohexanone) oxalyldihydrazone should be handled with care to avoid health risks. Direct contact with skin or eyes can cause irritation, and inhalation of dust should be prevented. Appropriate personal protective equipment (PPE), including gloves, goggles, and lab coats, is recommended when working with this compound. In case of exposure, affected areas should be rinsed thoroughly with water, and medical advice sought if necessary. Storage conditions are critical to maintaining the compound’s stability. It should be kept in a tightly sealed container in a cool, dry place, away from light and moisture. Prolonged exposure to air or humidity can lead to degradation, reducing its effectiveness as a reagent. Proper labeling and segregation from incompatible substances, such as strong acids or oxidizers, are also essential to ensure safety and longevity.
B2B Procurement Guide
For B2B buyers, sourcing bis(cyclohexanone) oxalyldihydrazone requires attention to purity, supplier reliability, and pricing. The compound is typically available in gram to kilogram quantities, with prices ranging from approximately $50 to $200 per gram, depending on purity and supplier. Buyers should request a Certificate of Analysis (CoA) to verify the product’s purity, which is often 95% or higher for analytical-grade material. Bulk purchases may qualify for discounts, so it’s advisable to negotiate with suppliers for larger orders. Leading chemical suppliers and specialized reagent distributors are the best sources for this compound. Buyers should also consider logistics, such as shipping conditions and lead times, to ensure timely delivery. Verifying the supplier’s compliance with safety and regulatory standards is another critical step in the procurement process.
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