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Biotin Hydrobromide

Updated: 2026-07-20

Overview

Biotin Hydrobromide is a chemical derivative of biotin (vitamin B7), where biotin is combined with hydrogen bromide to form a stable salt. This modification enhances certain physical properties of biotin, particularly its solubility in aqueous solutions, while maintaining its biological activity. The compound is primarily utilized in research settings and pharmaceutical manufacturing where the improved solubility characteristics are advantageous. It serves as an important intermediate in the synthesis of various biotin-containing compounds and finds application in biochemical assays and diagnostic procedures.

Physical and Chemical Properties

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Biotin Hydrobromide typically presents as a white to off-white crystalline powder with good solubility in water and polar organic solvents. The addition of hydrogen bromide to biotin modifies its physical properties without significantly altering its core molecular structure. The compound is hygroscopic, meaning it readily absorbs moisture from the air, which necessitates careful storage conditions. Its stability is generally good when stored properly, though prolonged exposure to heat, light, or moisture should be avoided to prevent degradation.

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Main Applications

In biochemical research, Biotin Hydrobromide is frequently employed as a more soluble alternative to free biotin in various experimental protocols. Its enhanced solubility makes it particularly valuable in aqueous-based systems where biotin's native solubility limitations might otherwise pose challenges. The pharmaceutical industry utilizes this compound as an intermediate in the production of certain medications and diagnostic agents. It also finds use in the formulation of specialized vitamin supplements where the improved solubility profile offers formulation advantages over standard biotin preparations.

Safety and Storage

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While Biotin Hydrobromide is not considered highly hazardous, standard laboratory precautions should be observed when handling this chemical. Appropriate personal protective equipment including gloves and safety glasses is recommended to prevent potential irritation from prolonged or repeated exposure. For long-term storage, the material should be kept in a tightly sealed container in a cool, dry environment, preferably under inert atmosphere when possible. Protection from light and moisture is essential to maintain product integrity over time. The hygroscopic nature of the compound makes proper storage particularly important.

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B2B Procurement Guide

When sourcing Biotin Hydrobromide for commercial or research purposes, several factors warrant careful consideration. Purity specifications should be verified against intended use requirements, with analytical certificates of analysis reviewed for batch-to-batch consistency. Procurement professionals should evaluate supplier reliability, material traceability, and compliance with relevant quality standards. Transportation conditions should ensure product stability, particularly for international shipments where temperature and humidity control may be necessary. Bulk purchasing may offer cost advantages, but stability considerations should guide inventory management practices.

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