Overview
Beta-Elemene is a naturally occurring sesquiterpene derived from various plants, including Curcuma wenyujin and ginger. It is known for its volatile, lipophilic nature and has gained attention in the pharmaceutical industry, particularly for its potential antitumor properties. Research suggests that Beta-Elemene may inhibit cancer cell proliferation and induce apoptosis, making it a candidate for adjunctive cancer therapy. It is also used in fragrances and flavorings due to its mild, woody aroma.
Physical and Chemical Properties
Beta-Elemene is a colorless to pale yellow oily liquid with a molecular weight of 204.35 g/mol. It is insoluble in water but dissolves readily in organic solvents like ethanol and ether. Its boiling point ranges between 254-256°C, and it has a low melting point of -15°C to -10°C. The compound is stable under normal conditions but should be protected from light and oxidizing agents to prevent degradation. Its lipophilic nature makes it suitable for formulation in lipid-based drug delivery systems.
Main Applications
The primary application of Beta-Elemene is in the pharmaceutical sector, where it is studied for its potential to treat cancers such as lung, liver, and glioblastoma. Clinical trials in China have explored its use in injectable formulations for tumor therapy. Beyond medicine, Beta-Elemene is used in the fragrance industry to add woody notes to perfumes and in food flavorings. Its low toxicity and natural origin make it appealing for these applications.
Safety and Storage
Beta-Elemene should be handled with care to avoid skin or eye irritation. Proper ventilation is recommended when working with the compound, and personal protective equipment (PPE) such as gloves and goggles should be worn. Storage requires a cool, dry environment away from direct sunlight and oxidizing agents. Containers should be tightly sealed to prevent evaporation and contamination. For large-scale procurement, inert gas (e.g., nitrogen) padding may be used to enhance stability.
B2B Procurement Guide
When sourcing Beta-Elemene, prioritize suppliers with certifications (e.g., GMP, ISO) and transparent quality control measures. Request certificates of analysis (CoA) to verify purity, typically ≥98% for pharmaceutical use. Bulk pricing varies by purity and quantity; negotiate contracts with reliable manufacturers in China or India, where production is concentrated. Consider regulatory requirements for your region, especially if the compound is intended for medical use.
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