Overview
Bacillus subtilis is a rod-shaped, Gram-positive bacterium that is commonly found in soil and vegetation. It is known for its ability to form spores, which allow it to survive in harsh environmental conditions. This bacterium is non-pathogenic and is widely used in various industrial applications due to its ability to produce enzymes, antibiotics, and other bioactive compounds. Bacillus subtilis is also a model organism for studying bacterial physiology and genetics. Its genome has been fully sequenced, making it a valuable tool for research in molecular biology and biotechnology. The bacterium's robustness and ease of cultivation make it a preferred choice for both academic and industrial applications.
Physical and Chemical Properties
Bacillus subtilis is a Gram-positive bacterium, meaning it retains the crystal violet stain used in the Gram staining procedure. It is catalase-positive, which means it can break down hydrogen peroxide into water and oxygen. The bacterium is aerobic, requiring oxygen for growth, but it can also grow under anaerobic conditions by using nitrate as an electron acceptor. The spores of Bacillus subtilis are highly resistant to heat, radiation, and chemicals, making them ideal for use in sterilization studies and as probiotics. The bacterium produces a variety of enzymes, including amylases, proteases, and lipases, which are used in industrial processes such as detergent manufacturing and food processing.
Main Applications
Bacillus subtilis is widely used in agriculture as a biofertilizer and biocontrol agent. It promotes plant growth by fixing nitrogen, solubilizing phosphorus, and producing phytohormones. The bacterium also suppresses plant pathogens by producing antibiotics and competing for nutrients. In the biotechnology industry, Bacillus subtilis is used to produce enzymes and antibiotics. It is a common host for recombinant protein production due to its ability to secrete proteins into the culture medium. In the pharmaceutical industry, the bacterium is used to produce antibiotics such as bacitracin and surfactin, which have antimicrobial properties.
Safety and Storage
Bacillus subtilis is generally recognized as safe (GRAS) by regulatory agencies such as the FDA and EFSA. However, standard microbiological precautions should be followed when handling the bacterium, especially in laboratory settings. This includes wearing gloves, lab coats, and eye protection. The bacterium should be stored in a cool, dry place away from direct sunlight. Spores of Bacillus subtilis are highly stable and can be stored for long periods without losing viability. For industrial use, the bacterium is often supplied as a lyophilized powder, which should be rehydrated with sterile water before use.
B2B Procurement Guide
When procuring Bacillus subtilis for industrial or research purposes, it is important to consider the strain type, purity, and intended application. Suppliers should provide a certificate of analysis (CoA) that includes information on the strain's identity, purity, and viability. Price can vary depending on the form (e.g., lyophilized powder, liquid culture) and the strain's specific properties. It is advisable to request samples from multiple suppliers to compare quality and performance. Additionally, ensure that the supplier complies with relevant regulatory standards, especially if the bacterium will be used in food, pharmaceutical, or agricultural applications.
Related Manufacturers
- 主营：科研试剂、高效试剂
- 主营：研突破、转座酶、重组酶、连接酶、研试剂、(5×)(with、recombinant、结合蛋白、胶体染料、核酸染料、助力科研、大肠杆菌、泛素蛋白、实验室用品、重组肠激酶、电泳缓冲液、拓扑异构酶、热敏磷酸酶、检测试剂盒、全能核酸酶、核酸外切酶、核酸内切酶、连接试剂盒、碱性磷酸酶、微球菌核酸酶
- 主营：抗体、感受态、培养基、试剂盒、层析柱、填料、生物试剂、化学试剂
- 主营：微生物菌种、标准菌株、益生菌、食用菌
- 主营：保鲜剂、活性炭、色素炭黑、洗涤原料、优级白砂糖、速溶硅酸钠、锅炉水处理、表面活性剂、聚合氯化铝、机油过滤砂、食品级防腐剂、工业级醋酸钠、玻璃钢用炭黑、净水处理絮凝剂
- 主营：AES、AOS、一水葡萄糖、果葡糖浆、过磷酸钙、海藻精、红糖、滑石粉、工业盐、矿源黄腐酸钾、磷酸一铵、硫酸铵、硫酸钾、硫酸锰、硫酸铜、氯化钾、麦芽糊精、麦芽糖浆、锚固剂、水玻璃、无水葡萄糖、氧化钙、一水柠檬酸
- 主营：微生物菌剂、饲料添加剂、丁酸梭菌、枯草芽孢杆菌、芽孢杆菌、解淀粉芽孢杆菌、巨大芽孢杆菌、侧孢芽孢杆菌、粪肠球菌、发酵菌、粪便发酵剂、双歧杆菌、乳杆菌、饲料添加剂微生物、EM菌、水产芽孢、秸秆腐熟剂、EM、酿酒酵母、长枝木霉
- 主营：枯草芽孢杆菌、锅炉除垢剂
- 主营：igg抗体、糖蛋白、试剂盒、脂蛋白、人瘦素、粗纤维、猪睾酮、烯二酮、nad激酶、测试盒、牛瘦素、牛胆酸、原果胶、磷酸酶、犬肾素、含水量、人蛋白、甜菜碱、igm抗体、dna抗体、磷脂酶、大鼠超、犬叶酸、人胆酸、样受体
- 主营：氧化剂、消毒剂、冰醋酸、复合枯草芽孢杆菌、辉腾化工、大棚氮肥、复配液体、腐殖酸钠、农业肥料、农用氮肥、过碳酸钠、氨基酸原粉、熏蒸剂颗粒、过氧碳酸钠、硫酸铜供应商
- 主营：矿源黄腐酸钾、氨基酸原粉、木质素磺酸钠、枯草芽孢杆菌、木质素磺酸钙、大苏打、腐殖酸钠、工业葡萄糖、工业白糖、工业红糖、黄腐酸钾、大蒜油、高铁酸钾、海藻精、过硫酸氢钾、腐植酸钠、氨氮去除剂、小苏打、鱼蛋白、EM菌
- 主营：醋酸可、杀菌剂、锚固剂、枯草芽孢杆菌、除草剂、洗涤剂、凡士林、硫酸铜、胺鲜酯、柠檬酸、絮凝剂、硫酸铵、增稠剂、糖蜜粉、取暖炉、催化剂、类香精、磷酸钠、漂白粉、防腐剂、洗手液、耐燃烧、叶面肥、桂皮酸、工业车、缓凝剂
- 主营：石墨烯、甘油、片碱、钛白粉、USP级甘油、聚合氯化铝、软水盐、小苏打、乙二醇、融雪剂、甲缩醛、液碱、氨水、草酸、DMF
- 主营：泡花碱、工业淀粉、矿源黄腐酸钾、枯草芽孢杆菌、工业葡萄糖、工业柠檬酸、固化剂、氨基酸原粉、工业红糖、大苏打
- 主营：酪蛋白酸钠 酪朊酸钠、氯化胆碱、甜菜碱、枯草芽孢杆菌厂家、酵母浸粉、蛋白胨、低聚果糖、低聚木糖、甘露寡糖、菊粉、D-异抗坏血酸钠、ε-聚赖氨酸、ε-聚赖氨酸盐酸盐、乳酸链球菌素、BHA 丁基羟基茴香、茶多酚 绿茶提取物、阿拉伯胶、刺槐豆胶、瓜尔豆胶 瓜尔胶、果胶 高酯果胶 低酯、海藻酸钠、黄原胶、结冷胶 低酰基结冷胶、聚丙烯酸钠
- 主营：ELISA试剂盒、PCR试剂盒、生化试剂盒、科研试剂
- 主营：次氯酸钠、大苏打、硫代硫酸钠、防冻剂、速溶硅酸钠、五水偏硅酸钠、零水偏硅酸钠、管道疏通剂、氯化钙、增氧片、过硫酸氢钾复合盐、二氧化氯、氨水、软水盐、氧化钙、草酸、小苏打、洗衣粉、过碳酸钠、爆炸盐、焦亚硫酸钠、液体草酸、过硫酸氢钾片、乙二醇、离子钙
- 主营：食品添加剂、饲料添加剂、营养强化剂、增稠剂、乳化剂、防腐剂、色素、磷酸盐保水剂、黄原胶、甘氨酸、酪蛋白酸钠、大豆分离蛋白、海藻酸钠、乳清蛋白粉、L-半胱氨酸、L-苯丙氨酸、L-异亮氨酸、丝氨酸、谷氨酰胺
- 主营：复合维生素、阿拉伯胶、刺槐豆胶、枯草芽孢杆菌厂家、瓜尔豆胶 瓜尔胶、果胶、海藻酸钠、黄原胶、结冷胶 低酰基结冷胶、聚丙烯酸钠、卡波姆、卡拉胶、可得然胶、魔芋粉、琼脂 琼脂粉、羧甲基纤维素钠、明胶、温轮胶 威兰胶、聚维酮K30、乙基纤维素、D-氨基葡萄糖盐酸盐、壳聚糖、壳寡糖、酪蛋白 干酪素