Overview
Benzyl azide is an organic compound with the molecular formula C7H7N3. It is widely used in chemical synthesis, particularly in click chemistry and as a pharmaceutical intermediate. Its reactive azide group makes it valuable for creating complex molecules in research and industrial applications. Due to its versatility, benzyl azide is a common reagent in laboratories and pharmaceutical manufacturing. It is typically handled with caution due to its potential explosiveness under specific conditions, requiring proper storage and handling protocols.
Physical and Chemical Properties
Benzyl azide appears as a colorless to pale yellow liquid with a density of approximately 1.08 g/cm³. It is soluble in common organic solvents such as ethanol and ether, making it easy to work with in laboratory settings. The compound is known for its high reactivity, particularly in click chemistry reactions where it forms stable triazole compounds. Its molecular weight is 133.15 g/mol, and it should be stored away from heat and direct sunlight to prevent decomposition or hazardous reactions.
Main Applications
Benzyl azide is primarily used in pharmaceutical synthesis, where it serves as an intermediate for creating active pharmaceutical ingredients (APIs). It is also employed in polymer chemistry to modify or crosslink polymers, enhancing their properties. In research, benzyl azide is a key reagent in click chemistry, enabling the rapid and efficient synthesis of complex molecules. Its applications extend to material science, where it is used to functionalize surfaces or create specialized coatings.
Safety and Storage
Benzyl azide is a hazardous compound and should be handled with extreme care. It may explode under certain conditions, such as exposure to heat or shock. Proper personal protective equipment (PPE), including gloves and goggles, is essential when working with this chemical. Storage should be in a cool, dry place, away from direct sunlight and heat sources. Containers must be tightly sealed and labeled correctly to prevent accidental exposure or misuse. Disposal should follow local regulations for hazardous waste.
B2B Procurement Guide
When procuring benzyl azide, buyers should verify the CAS number (622-79-7) and purity specifications to ensure product quality. Reputable suppliers with certifications (e.g., ISO) are preferred for consistent quality and safety. Bulk orders may offer cost savings, but buyers should confirm storage and handling requirements beforehand. Pricing varies by purity and supplier, with laboratory-grade typically ranging from $50 to $200 per gram. Always request safety data sheets (SDS) and certificates of analysis (CoA) before purchase.
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