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Atractylodes Extract

Updated: 2026-07-23

Overview

Atractylodes Extract is obtained from the rhizomes of Atractylodes lancea (Cangzhu) or Atractylodes macrocephala (Baizhu), perennial herbs native to East Asia. It has been a cornerstone of traditional Chinese medicine for centuries, primarily valued for its digestive and anti-inflammatory properties. Modern extraction techniques isolate bioactive compounds like atractylenolides, sesquiterpenes, and polysaccharides, which contribute to its therapeutic effects. The extract is commercially available in powder or liquid form, standardized to specific active compound concentrations. Its applications span pharmaceuticals (e.g., gastrointestinal drugs), nutraceuticals (digestive aids), and cosmetics (anti-aging formulations). Quality varies by source plant species, extraction method (e.g., water, ethanol, or supercritical CO2), and purity, making supplier verification critical for B2B buyers.

Physical and Chemical Properties

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Atractylodes Extract typically appears as a brownish-yellow hygroscopic powder with a characteristic earthy odor. Its solubility profile allows it to blend well in aqueous or alcohol-based formulations, though precipitation may occur in high concentrations. Key markers like atractylenolide III (CAS 73030-71-4) are often quantified via HPLC to standardize potency, with commercial grades ranging from 2% to 20% active content. The extract is stable under recommended storage conditions but may degrade when exposed to high humidity or temperatures above 30°C. Its polysaccharide fraction contributes to immunomodulatory effects, while volatile oils (e.g., β-eudesmol) are linked to anti-inflammatory activity. pH stability ranges from 4 to 8, making it compatible with most formulation matrices.

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Main Applications

In pharmaceuticals, Atractylodes Extract is incorporated into formulas for treating diarrhea, indigestion, and inflammatory conditions like arthritis. Its ability to modulate gut microbiota and enhance digestive enzyme secretion makes it a popular ingredient in TCM prescriptions such as Shenling Baizhu San. Clinically, atractylenolides show promise in cancer adjuvant therapy due to their anti-proliferative effects. The nutraceutical industry uses it in capsules or teas for metabolic health, often combined with ginger or licorice. Cosmetic applications leverage its antioxidant properties in anti-aging serums and acne treatments. Emerging research explores its potential in veterinary medicine (e.g., poultry growth promotion) and functional foods, though regulatory approvals vary by region.

Safety and Storage

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Atractylodes Extract is generally safe within recommended dosages (typically 50-500 mg/day for supplements), though excessive intake may cause dry mouth or dizziness. Allergic reactions are rare but possible in sensitive individuals. Occupational exposure guidelines recommend dust masks when handling powder forms to prevent respiratory irritation. Proper storage involves airtight containers with desiccants to prevent moisture absorption. Bulk quantities should be palletized in a climate-controlled warehouse. Shelf life is typically 2-3 years when stored correctly, though retesting after 12 months is advisable for critical applications. Disposal should follow local regulations for organic plant materials.

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B2B Procurement Guide

When sourcing Atractylodes Extract, prioritize suppliers with GMP certification and transparent supply chains. Request batch-specific Certificates of Analysis (COA) verifying active compound levels (e.g., atractylenolide III ≥5% for premium grades), heavy metal content (<10 ppm lead), and microbial limits. HPLC or UV testing reports add credibility. For large orders (100+ kg), negotiate tiered pricing and confirm MOQs. Consider extraction method differences: ethanol extracts yield higher atractylenolide concentrations but cost 20-30% more than water extracts. Logistics should prioritize temperature-controlled shipping for liquid forms. Sample testing for solubility and stability in your final formulation is strongly recommended before full-scale procurement.

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