Overview
Artificial urine is a synthetic solution engineered to replicate the chemical composition and physical characteristics of human urine. It is primarily used in medical and scientific settings where consistent and controlled urine samples are required. Unlike natural urine, its composition can be precisely adjusted to meet specific testing or calibration needs. Common formulations include water, urea, creatinine, salts (e.g., NaCl, KCl), and pH buffers to match natural urine's properties. Some advanced versions may also contain glucose, proteins, or metabolites for specialized applications. The solution is sterile and free from biological contaminants, making it safer for laboratory use.
Physical and Chemical Properties
Artificial urine is designed to closely match the density (1.005–1.030 g/cm³), pH (4.5–8.0), and electrolyte balance of natural urine. Its osmolarity typically ranges between 50–1200 mOsm/kg, adjustable for specific testing requirements. The solution is stable under refrigeration but may degrade if exposed to heat or light over time. Key components include urea (the primary nitrogenous waste) at concentrations of 9–23 g/L and creatinine (0.67–2.15 g/L). Trace elements like sodium, potassium, and phosphate ions are added to simulate physiological levels. Variations exist for niche applications, such as drug-testing validation, where metabolites like THC-COOH may be included.
Main Applications
In diagnostics, artificial urine is critical for calibrating urinalysis devices, ensuring accurate readings for glucose, protein, and pH levels. It serves as a control sample to validate equipment performance in clinical laboratories. Researchers also use it to study urinary tract infections (UTIs) or kidney diseases without relying on volatile biological samples. The pharmaceutical industry employs synthetic urine in drug development, particularly for testing excretion rates or dialysis efficiency. Educational institutions use it for hands-on training in medical and chemistry programs. Notably, it has controversial off-label uses in drug-testing evasion, prompting stricter formulation controls in some regions.
Safety and Storage
While non-pathogenic, artificial urine should be handled with standard laboratory precautions, including gloves and eye protection. Some formulations may contain chemical analogs that mimic biohazards, requiring disposal as regulated waste. Avoid ingestion or skin contact, though toxicity is generally low. Storage requires refrigeration (2–8°C) in tightly sealed, light-resistant containers to prevent evaporation or microbial growth. Shelf life varies by formulation but typically ranges from 6 months to 2 years. Always check manufacturer guidelines for stability data and incompatibilities with certain testing methods (e.g., enzyme-based assays).
B2B Procurement Guide
Bulk buyers should prioritize suppliers with ISO 13485 certification for diagnostic-grade products or GMP compliance for pharmaceutical applications. Custom formulations are often available for specialized needs, such as elevated protein levels for nephrology research. Pricing depends on volume and complexity; bulk orders (100+ liters) may reduce costs by 30–50%. Request Certificates of Analysis (CoA) for each batch to verify composition. For international shipments, confirm compliance with regional regulations—some countries restrict synthetic urine sales due to misuse concerns. Lead times vary but average 2–4 weeks for custom orders.
Related Manufacturers
- 主营：透析袋、移液器、SIGMA、500ml人工尿液、赛默飞、爱思进、康宁、离心管、巴氏吸管、保存管、封板膜、细胞爬片、滤器、ELISA试剂盒
- 主营：透析袋、移液器、SIGMA、500ml人工尿液、赛默飞、爱思进、吸头/枪头、离心管、巴氏吸管、保存管、封板膜、细胞爬片、滤器、ELISA试剂盒
- 主营：硫酸铜、指示液、铁离子、锰离子、镁离子、缓冲液、硫酸镁、碘化钾、氯化钠、氯离子、蒸馏水、葡萄糖、氯化物、碳酸钠、钛离子、储备液、四苯硼钠、标准溶液、甲醛试纸、氢氧化钾、缓冲溶液、磷表试剂、草酸试剂、硫代乙酰胺、电脑水冷液
- 主营：染色液、碱性蓝、甘氨酸、玉米素、氯霉素、腺嘌呤、媒介蓝、抽提液、异烟酸、试剂盒、dtt溶液、糖原pas、酪蛋白、胆固醇、酚试剂、烟酰胺、牛磺酸、热灭活、奎尼丁、养乐多、碱性红、纤维素、皂化液、水合物、乳糖酸
- 主营：异硫氰酸胍、三(羟甲基)氨基甲烷tris、二硫苏糖醇(DTT)、β巯基乙醇、蛋白酶k、焦碳酸二乙酯DEPC、EDTA二钠、十二烷基苯磺酸钠
- 主营：生化试剂、细胞生物学、培养基、酶活检测试剂盒
- 主营：染色液、甘氨酸、固紫酱、人工尿液、玉米素、饱和酚、甘露醇、修复液、试剂盒、脂蛋白、指示剂、肌氨酸、丙基红、酪蛋白、地衣红、胆固醇、磷钼酸、铝试剂、牛磺酸、混合物、七叶苷、新品红、赖氨酸、纤维素、皂化液、溴酚红
- 主营：生物dna、dna病毒、dna回收、低浓度质控人工尿液、植物dna、dna产物、基因组dna、小提试剂盒、提取试剂盒、两步法细菌、离心柱式血液、酵母质粒提取、蛋白浓度测定、细胞增殖检测
- 主营：医药中间体、香精香料、硅烷偶联剂、人工尿液、氧化石蜡皂、苯乙烯磷酸、苯甲羟肟酸、H205、阻聚剂706、阻聚剂701、萤石矿捕收剂、白钨矿捕收剂、稀土矿捕收剂、氧化锑矿捕收剂、活化剂
- 主营：医药中间体、香精香料、选矿药剂、人工尿液、化工原料、助剂、偶联剂、扩链剂、化妆品原料
- 主营：捕收剂、液体聚硫橡胶、染料中间体、扩链剂、催化剂、交联剂、稳定剂、辅助剂、中间体、碳酸镍、抗氧化剂、乙酰丙酮锰、羟基保护剂、表面活性剂、四甲基氯化铵、分子筛模板剂、溶剂型防锈漆、四乙基氯化铵、正癸基硫酸钠、药物合成原料、氧化石蜡皂、水杨羟肟酸、阻聚剂706、克利夫酸
- 主营：生化试剂、蛋白与免疫、ELISA、生化试剂盒、染色试剂、微生物培养、磁珠、纳米材料、抗体
- 主营：涂料助剂、工业清洗剂、表面活性剂、人工尿液、合成材料助剂、合成香料、溶剂、香精和香料中间、合成材料中间体、选矿药剂、萃取剂
- 主营：草铵膦、恶霜灵、雌酚酮、人工尿液、溴虫腈、标准品、氟环唑、苯甲酸、大观霉素、恶唑菌酮、异丙氧磷、多拉菌素、氘代甲苯、呋喃西林、氟罗沙星、3-二氯丙烯、吡氟氯禾灵、二氯吡啶酸、二甲基吗啉、一氯二溴甲烷、硝基呋喃妥因
- 主营：D-荧光素钾、D-荧光素钠、缓冲液、人工尿液、裂解液、脲酶Urease、刀豆凝集素ConA、黄嘌呤氧化酶、胰α淀粉酶、β-葡萄糖苷酶、辣根过氧化物酶、生化试剂盒、tRNA转运核糖核酸、胰蛋白酶抑制剂、乙酰胆碱酯酶、L-乳酸脱氢酶、过氧化氢酶、葡萄糖氧化酶、肝素钠、福林酚、三羟甲基氨基甲烷、二硫苏糖醇DTT、苏木色精、伊红Y(曙红)、乙基紫