Overview
Diapigenin Standard is a purified flavonoid compound primarily used as a reference material in analytical chemistry and phytochemical research. As a dimer of apigenin, it occurs naturally in celery and related plants, though the standard is typically produced through isolation or synthesis to achieve pharmaceutical-grade purity. This standard plays a crucial role in quality control for herbal products and nutraceuticals, particularly those containing celery seed extract. Laboratories rely on it for method validation, compound identification, and quantitative analysis in various chromatographic techniques.
Physical and Chemical Properties
Diapigenin appears as a fine crystalline powder with a light yellow to off-white coloration. The compound demonstrates characteristic UV absorption maxima between 270-340 nm, making it suitable for HPLC detection with UV/Vis or PDA detectors. As a flavonoid dimer, diapigenin exhibits moderate polarity and shows better solubility in organic solvents like dimethyl sulfoxide (DMSO) and methanol than in water. The compound is relatively stable when stored properly but may degrade under prolonged exposure to light, heat, or oxidizing conditions.
Main Applications
In pharmaceutical research, diapigenin standard serves as a critical marker compound for analyzing celery-based preparations and botanical extracts. It helps validate analytical methods for content determination and fingerprint analysis in traditional Chinese medicine formulations. The standard also finds use in antioxidant capacity studies, as diapigenin demonstrates free radical scavenging activity. Research laboratories employ it in pharmacokinetic studies to understand the absorption and metabolism of flavonoid compounds in biological systems.
Safety and Storage
While diapigenin itself shows low acute toxicity, standard laboratory precautions should be followed. Use gloves and eye protection when handling, and avoid creating airborne dust. In case of contact, flush eyes/skin with plenty of water. For long-term stability, store the standard in amber glass vials with PTFE-lined caps at -20°C. Allow containers to reach room temperature before opening to prevent moisture condensation. The material should be protected from strong oxidizers and extreme pH conditions.
B2B Procurement Guide
When sourcing diapigenin standard, prioritize suppliers that provide comprehensive analytical documentation, including a certificate of analysis with batch-specific purity data (preferably ≥98%), HPLC chromatogram, and mass spectrum. Reputable manufacturers should offer stability data and storage recommendations. For research institutions requiring traceability, consider suppliers who can provide the compound's origin information (natural isolation or synthetic preparation) and any available pharmacokinetic or toxicity data. Bulk purchases (100mg+) typically offer better value but verify storage capacity and projected usage rates first.
Related Manufacturers
- 主营：桉油精、薄荷脑、中药对照品、标准品、白花前胡丙素、白藜芦醇三甲醚
- 主营：钩藤碱、丹皮酚、c17h26o10、管花苷、白麻苷、络石苷、木皂苷、皂苷rg2、芹菜素、高良姜、丹参酮、鞣花酸、川楝素、苍术素、芦竹碱、苦参碱、土贝母、柚皮素、甜菜碱、紫草素、苏木素、甘露糖、番茄碱、青蒿酸、紫杉醇
- 主营：对照品、科研实验、试剂盒、安石榴苷、人参皂苷、黄芪皂苷系列、多糖、儿茶素、绿原酸、尿石素、花青素、维生素、异鼠李素、甘草系列、人参系列、补骨脂系列、雷公藤系列、黄芩系列、柴胡系列、丹参系列、酸枣仁系列、重楼系列、大黄系列、五味子系列、化合物
- 主营：对照品、中药多糖、检验检测服务、标准品、中药研究服务、CMO/CDMO
- 主营：桤木酮、香附酮、1617-70-5、皂苷rd2、管花苷、白麻苷、木皂苷、皂苷rg3、苷甲酯、苍术素、2586-96-1、松脂素、dl-醉椒、柯诺辛、苜蓿素、夹竹桃、7729-23-9、5928-25-6、化合物、口山酮、3668-14-2、异甘草、脱氧马、刺五加、2292-16-2
- 主营：甲基原、钩藤碱、络塞定、管花苷、白麻苷、秦皮苷、葛花苷、柚皮苷、丹皮酚、2086-83-1、6836-11-9、鞣花酸、川楝素、黄芩素、苍术素、松脂素、熊果酸、苦参碱、6926-08-5、土莫酸、苜蓿素、茯苓酸、柚皮素、3668-14-2、山奈酚
- 主营：细辛脂素、百两金素、延胡索乙素、标准品、桃叶珊瑚苷、脱氢紫堇碱
- 主营：龙胆苦苷、獐牙菜苦苷、杨梅苷、粉防己碱