Overview
Isodin, chemically known as 6,8-Diprenylnaringenin, is a naturally occurring flavonoid derived from plants such as hops (Humulus lupulus) and celery (Apium graveolens). It belongs to the prenylated flavonoid class, characterized by its unique molecular structure with two prenyl groups. This compound has garnered attention in scientific research due to its bioactive properties, including antioxidant and anti-inflammatory effects. Flavonoids like Isodin are studied for their potential role in mitigating oxidative stress and inflammation-related diseases. Its natural origin and promising pharmacological profile make it a subject of interest for pharmaceutical and nutraceutical applications. Research is ongoing to explore its full therapeutic potential, particularly in neuroprotection and cancer prevention.
Physical and Chemical Properties
Isodin is a pale yellow crystalline powder with a molecular weight of 406.47 g/mol. It is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol but exhibits limited solubility in water. The compound has a melting point range of approximately 160-165°C, which is typical for flavonoids of its class. Its chemical stability is influenced by environmental factors like light and humidity, necessitating proper storage conditions. The presence of prenyl groups in its structure enhances its lipophilicity, which may improve bioavailability and membrane permeability. These properties are critical for its potential applications in drug formulation and functional food development.
Main Applications
Isodin is primarily utilized in pharmaceutical and nutraceutical research. Its antioxidant properties make it a candidate for developing therapies targeting oxidative stress-related conditions, such as neurodegenerative diseases and cardiovascular disorders. Additionally, its anti-inflammatory effects are being explored for potential use in treating chronic inflammatory diseases. In the nutraceutical industry, Isodin is investigated as an ingredient in functional foods and dietary supplements aimed at promoting health and preventing disease. Its natural origin aligns with the growing consumer demand for plant-based bioactive compounds. Research also suggests its potential as an adjunct in cancer therapy, though clinical studies are needed to validate these findings.
Safety and Storage
While Isodin is derived from natural sources, proper handling is essential to ensure safety. Laboratory personnel should avoid inhalation, ingestion, or direct skin contact. Personal protective equipment (PPE), including gloves and goggles, is recommended when handling the compound. Storage conditions play a crucial role in maintaining its stability. Isodin should be stored in a tightly sealed container, protected from light, moisture, and extreme temperatures. Ideal storage temperatures range between 2-8°C for long-term preservation. Suppliers often provide material safety data sheets (MSDS) that outline specific handling and storage guidelines.
B2B Procurement Guide
For B2B buyers, sourcing high-quality Isodin requires careful consideration of purity, supplier reliability, and cost. High-performance liquid chromatography (HPLC) analysis should confirm a purity level of ≥98% for research-grade material. Reputable suppliers often provide certificates of analysis (CoA) to verify quality. Bulk purchases may offer cost advantages, with prices typically ranging from $50 to $200 per gram, depending on quantity and purity. Buyers should evaluate supplier credentials, including manufacturing practices and customer reviews, to ensure consistent quality. Custom synthesis options are available for specialized research needs, though lead times and costs may vary.
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