Andrographolide e

Updated: 2026-09-18

Overview

Andrographolide e is a bioactive compound extracted from Andrographis paniculata, a medicinal plant widely used in traditional medicine. It belongs to the class of labdane diterpenoids and is noted for its potent pharmacological effects. The compound has garnered attention for its potential therapeutic applications, particularly in treating inflammatory and infectious diseases. Research into Andrographolide e has highlighted its role in modulating immune responses and inhibiting viral replication. Its ability to interact with various biological pathways makes it a promising candidate for drug development. The compound is typically isolated through advanced extraction and purification techniques to ensure high purity and efficacy.

Physical and Chemical Properties

Andrographolide e is commonly found as a white to off-white crystalline powder. It is soluble in organic solvents like ethanol and dimethyl sulfoxide (DMSO), but has limited solubility in water. The compound's stability is influenced by environmental factors such as temperature and humidity, necessitating proper storage conditions to maintain its integrity. While detailed physicochemical data such as melting and boiling points are not widely documented, the compound's molecular structure contributes to its bioactivity. Its labdane skeleton is key to its interaction with biological targets, enabling its diverse pharmacological effects.

Main Applications

Andrographolide e is primarily used in the pharmaceutical and nutraceutical industries. Its anti-inflammatory and immunomodulatory properties make it valuable for developing treatments for conditions like arthritis, respiratory infections, and autoimmune disorders. Additionally, its antiviral activity has been explored for potential use in antiviral therapies. Beyond therapeutics, Andrographolide e is utilized in research to study its mechanisms of action and potential new applications. Its inclusion in dietary supplements is also gaining traction, driven by consumer interest in natural health products. The compound's versatility underscores its importance in both clinical and commercial settings.

Safety and Storage

Proper handling and storage of Andrographolide e are essential to ensure its stability and safety. The compound should be stored in a cool, dry environment, away from direct light and moisture. Exposure to adverse conditions can degrade its quality and reduce its efficacy. Safety precautions include wearing protective gear such as gloves and goggles when handling the compound. Inhalation or skin contact should be avoided, as it may cause irritation. In case of accidental exposure, immediate rinsing with water and seeking medical advice is recommended. Always refer to the material safety data sheet (MSDS) for specific guidelines.

B2B Procurement Guide

When procuring Andrographolide e, B2B buyers should prioritize quality and reliability. Key considerations include verifying the supplier's credentials and requesting a Certificate of Analysis (COA) to confirm purity and composition. Reputable suppliers often provide detailed product specifications and batch testing results. Pricing can vary significantly based on purity levels and order quantities. Buyers are advised to compare offerings from multiple suppliers and negotiate bulk purchase discounts where possible. Additionally, ensure that the supplier complies with relevant regulatory standards to guarantee product safety and efficacy.