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Aminophenyl

Updated: 2026-07-15

Overview

Aminophenyl, also known as 4-aminophenyl or p-aminophenyl, is an aromatic amine with the molecular formula C6H7N. It is a key intermediate in the synthesis of dyes, pharmaceuticals, and agrochemicals. The compound is characterized by the presence of an amino group attached to a benzene ring, which enhances its reactivity and utility in various chemical reactions. Aminophenyl is commonly used in industrial settings due to its ability to form diazonium salts, which are essential for azo dye production. Its versatility and reactivity make it a valuable building block in organic synthesis, particularly in the manufacture of complex molecules.

Physical and Chemical Properties

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Aminophenyl appears as a white to light yellow crystalline powder with a density of 1.18 g/cm³. It has a melting point of 186-188 °C and is soluble in organic solvents like ethanol and ether, but only slightly soluble in water. The compound's aromatic amine structure makes it reactive, particularly in electrophilic substitution reactions. The amino group in aminophenyl can participate in various chemical transformations, including diazotization, acylation, and alkylation. These properties are exploited in industrial processes to create derivatives for specific applications. Stability is a concern, as the compound can degrade when exposed to light or oxidizing agents, necessitating proper storage conditions.

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Main Applications

Aminophenyl is primarily used as an intermediate in the synthesis of azo dyes, which are widely employed in textiles, inks, and plastics. Its ability to form diazonium salts is critical for producing vibrant and stable dyes. The compound is also utilized in pharmaceutical manufacturing, where it serves as a precursor for drugs like sulfa antibiotics and analgesics. In the agrochemical industry, aminophenyl derivatives are incorporated into pesticides and herbicides. Its reactivity allows for the creation of compounds that target specific pests or weeds. Additionally, it finds use in research laboratories as a reagent for organic synthesis and chemical analysis.

Safety and Storage

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Aminophenyl is classified as toxic and can cause harm if ingested, inhaled, or absorbed through the skin. Proper personal protective equipment (PPE), such as gloves and goggles, should be worn when handling the compound. Adequate ventilation is essential to prevent inhalation of dust or vapors. Storage requires a cool, dry environment away from light and oxidizing agents to prevent degradation. Containers should be tightly sealed and labeled with hazard information. Spills should be cleaned up immediately using appropriate absorbent materials, and disposal must comply with local regulations to minimize environmental impact.

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B2B Procurement Guide

When procuring aminophenyl, businesses should prioritize suppliers with certifications like ISO or GMP to ensure product quality and consistency. Key specifications to verify include purity (typically 98-99%), moisture content, and the absence of impurities. Bulk purchases may offer cost advantages, but storage capabilities must be assessed beforehand. Logistics considerations include secure packaging to prevent contamination or degradation during transit. Buyers should also evaluate the supplier's track record for reliability and compliance with safety regulations. Establishing long-term contracts with reputable suppliers can ensure a steady supply chain and favorable pricing terms.

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