Aminoacetonitrile hydrogen sulfate
Overview
Aminoacetonitrile bisulfate (AAN bisulfate) is an organic salt formed from aminoacetonitrile and sulfuric acid. It serves as a versatile intermediate in chemical synthesis, particularly in pharmaceutical manufacturing. The compound is valued for its reactivity in Strecker amino acid synthesis and other nucleophilic addition reactions. Industrial production typically involves the reaction of aminoacetonitrile with sulfuric acid under controlled conditions.
Physical and Chemical Properties
As a crystalline solid, aminoacetonitrile bisulfate exhibits moderate solubility in polar solvents. Its molecular structure contains both nitrile and bisulfate functional groups, making it reactive in various chemical transformations. The compound's hygroscopic nature requires careful storage to prevent degradation. Thermal analysis shows decomposition beginning around 175°C, rather than a distinct melting point, which is characteristic of many organic salts.
Main Applications
Pharmaceutical manufacturers use aminoacetonitrile bisulfate as a key intermediate in producing various active pharmaceutical ingredients (APIs), particularly those containing glycine derivatives. In organic synthesis laboratories, it serves as a building block for heterocyclic compounds and specialty chemicals. Some agrochemical formulations also incorporate this compound as a precursor for certain pesticides and herbicides.
Safety and Storage
Proper handling of aminoacetonitrile bisulfate requires personal protective equipment including gloves, goggles, and lab coats. The compound can cause irritation upon contact with skin or eyes. Storage recommendations include airtight containers in cool (below 25°C), dry environments. Incompatible materials include strong bases, oxidizing agents, and reactive metals. Spills should be contained with inert absorbent materials and disposed of properly.
B2B Procurement Guide
When sourcing aminoacetonitrile bisulfate, buyers should specify required purity levels (typically 95-99%) and request certificates of analysis. Pharmaceutical-grade material requires additional documentation including GMP compliance certificates. Lead times may vary from 2-6 weeks depending on supplier inventory. Consider ordering smaller test quantities before committing to bulk purchases, especially when switching suppliers. Transportation regulations may apply due to the compound's chemical classification.
Related Manufacturers
- 主营：粘结剂、阻燃剂、絮凝剂、氨基乙腈硫酸氢盐、3584-23-4、引发剂、哌啶基、封端剂、乙交酯、抗菌剂、交联剂、肌肽锌、增亮剂、干燥剂、润滑剂、护发剂、粘合剂、对位酯、阻聚剂、稀释剂、羟乙基、偶联剂、分散剂、中间体、l-丙交酯、丙烯酸锌
- 主营：二乙烯基苯、烯丙基缩水甘油醚、氧化锂、3'-二氨基联苯、三羟甲基丙烷、4-三氮唑、丁二酸二异辛酯磺酸钠、四甲基己二胺、乙二醇二缩水甘油醚
- 主营：碱性蓝、碳化钒、霍霍巴、硫酸锰、锡酸钠、卵磷酯、1824-81-3、硼化锆、棉籽油、丙烯晴、松油醇、胆固醇、香茅酸、油酸钾、2103-99-3、磷酸铁、分散蓝、分子筛、莱菔素、四氮唑、氰酸钠、樱花亭、钨酸铋、水合物、甘油酸
- 主营：N-二甲基烯丙基、氯化偏苯三酸酐
- 主营：三聚甲醛、四甲基氢氧化胺、双季戊四醇、氨基磺酸、双乙烯酮、异丙叉丙酮、十一烷、硫氢化钠、甲基丙烯酸十八酯、四甲基氢氧化铵五水合物、水杨羟肟酸、异己二醇、苯甲羟肟酸、聚硫橡胶、甲基纤维素、环氧环己烷、硬脂酸乙二醇单酯、邻氯溴苯、二苯甲酮BP、均苯四甲酸二酐、月桂酸钠、吐温、司盘
- 主营：乙酸镁、并噻吩、三蝶烯、硫酸锂、硫酸锶、二乙烯、肌氨酸、嘧菌酯、碳酸镁、新癸酸、赖氨酸、多佐胺、咯菌腈、乙氧基、茚三酮、咖啡酸、氟苯基、α-氟萘、羟乙基、异恶唑、2223-82-7、喹啉黄、庚二酸、虫酰肼、吡咯并
- 主营：柠檬酸、蛋白酶k、卡波姆941、氨基乙腈硫酸氢盐、卡波姆940、羟乙基脲、邻香兰素、百里香酚、卡波姆1342、二甲苯青ff、异硫氰酸胍、醋酸氯己定、醋酸洗必泰、甘草酸二钾、甘宝素、二苯基二羟基硅烷
- 主营：阻燃剂、催化剂、洗涤剂、硫酸铵、醋酸镧、起泡剂、清洗剂、碳酸钙、抗氧剂、灭火剂、交联剂、粘合剂、封头剂、丙二醇、酸二氢铝、聚乙烯醇、对氯溴苯、生物试剂、息香乙醚、异戊二醇、香精香料、4-丁二醇、2-氯丙烯腈、2-己基癸酸、二甲胺硼烷
- 主营：2-乙烯基吡啶、氯甲酸苄酯、十八硫醇、4-二甲氨基吡啶、叔丁胺、3-环戊二烯、六甲基氧二硅烷、六氟磷酸铵、六氟磷酸
- 主营：三氟乙酸、三异丙基硅烷、三甲基氯硅烷、氨基乙腈硫酸氢盐、N-甲基吗啉、吩噻嗪、甲基叔丁基醚、吗啉、N-二异丙基乙胺、2-乙二硫醇、2-甲基四氢呋喃、DBU、四甲基乙二胺、3-巯基丙酸、五氯化钽、3-甲基吡啶、三苯基膦、二乙二醇二甲醚、三丁基膦、1-萘乙酮、3-丁炔-2-醇、6-二甲基吡啶、氯戊烷
- 主营：水苏糖、阻燃剂、玫瑰酯、硫酸锂、胶黏剂、百里酚、黄柏酮、四氢萘、溴壬烷、琥珀芯、磷酸铵、锑酸钠、牛磺酸、灭火剂、碳酸镍、特戊醛、蒸煮剂、咖啡酸、熟化剂、浮选剂、稀释剂、西瓜酮、甜昧剂、去除剂、乙硫氮
- 主营：氨基乙腈硫酸氢盐151、咪唑、原甲酸三乙酯、N-二甲基乙醇胺
- 主营：甲硫醇钠、甲基磺酸、六氟磷酸钠、氨基乙腈硫酸氢盐151、碳酸二甲酯、3-吡啶二甲酸、环己基苯、六氟磷酸钾、N-二甲基正辛胺
- 主营：氨基乙腈硫酸氢盐151、异丙醚、二甲基二氯硅烷、2-巯基苯并咪唑
- 主营：棕榈酸、乙酸铋、异喹啉、氨基乙腈硫酸氢盐、胶粘剂、丙烯酸酯、化学试剂、分析试剂、透明液体、二乙二醇、光引发剂、岩白菜素、对甲苯磺酸、苯甲酸苄酯、偏苯三酸酐、六氟异丙醇、纳米氧化铽、六氟磷酸铯、表面活性剂、蓖麻醇酸锌、乙基纤维素、荧光指示剂、2-乙二硫醇、4-二氟苄溴|、丙烯酸羟乙酯、3-丙烷磺内酯