Overview
Cyclopropylalanylglutamine (CPAG) is a synthetic dipeptide composed of cyclopropylalanine and glutamine residues. It is primarily used in biochemical research and pharmaceutical development. The compound is valued for its role in peptide synthesis and as an intermediate in drug discovery. CPAG is not naturally occurring and is typically produced through solid-phase peptide synthesis (SPPS) or solution-phase methods. Its stability and solubility make it suitable for various experimental applications, particularly in studying peptide interactions and metabolic pathways.
Physical and Chemical Properties
Cyclopropylalanylglutamine appears as a white to off-white crystalline powder with a molecular weight of 257.29 g/mol. It is hygroscopic and should be handled in a controlled environment to prevent moisture absorption. The compound decomposes at approximately 180-185°C, and its solubility in water makes it practical for laboratory use. Key chemical properties include its stability under recommended storage conditions and its reactivity in peptide bond formation. The presence of both cyclopropyl and glutamine moieties contributes to its unique structural and functional characteristics in biochemical applications.
Main Applications
CPAG is primarily utilized in pharmaceutical research as an intermediate in the synthesis of more complex peptides and peptidomimetics. Its structural features make it useful for studying peptide-protein interactions and designing bioactive compounds. In addition to pharmaceutical applications, CPAG is employed in biochemical assays to investigate metabolic pathways involving glutamine and cyclopropylalanine. Its role in drug discovery is particularly significant, as it can serve as a building block for novel therapeutics targeting specific enzymes or receptors.
Safety and Storage
Cyclopropylalanylglutamine should be handled with care to avoid inhalation or skin contact. Personal protective equipment (PPE), including gloves and lab coats, is recommended. The compound is not known to be highly toxic, but standard laboratory safety protocols should be followed. Storage conditions are critical to maintaining the stability of CPAG. It should be kept in a cool, dry place (2-8°C), protected from light and moisture. Long-term storage may require desiccants or inert atmospheres to prevent degradation.
B2B Procurement Guide
When procuring Cyclopropylalanylglutamine, buyers should prioritize suppliers with demonstrated expertise in peptide synthesis. Key considerations include purity levels (typically >98%), batch-to-batch consistency, and compliance with Good Manufacturing Practices (GMP) for pharmaceutical-grade material. Bulk procurement may involve custom synthesis, which requires clear specifications and lead time for production. Pricing varies based on quantity and purity, with laboratory-scale quantities commonly ranging from $50 to $200 per gram. Buyers should also verify supplier certifications and request analytical data (e.g., HPLC, MS) to ensure product quality.
Related Manufacturers
- 主营：生化试剂、蛋白与免疫、ELISA、生化试剂盒、染色试剂、微生物培养、磁珠、纳米材料、抗体
- 主营：反应活、hydrazide、修饰剂、谷氨酰胺、催化剂、糖蛋白、连接子、激动剂、聚合物、活性脂、胆固醇、钆特酸、催化性、dna标记、络合剂、荧光试剂、雨蛙素、乙二胺、ped结构、衍生物、化合物、链接剂、反应物、生物素
- 主营：多肽合成、抗体制备、蛋白表达
- 主营：对照品、标准品、当归酸酐、谷氨酰胺、佛手柑内酯、新当归内酯、补骨脂甲素、补骨脂乙素、羟基芍药苷、阿魏酸松柏酯、水合氧化前胡素、豆甾醇葡萄糖苷
- 主营：药品检测标准品、药物杂质标准品、对照品、中药对照药材、中药农残空白基质、分析标准品、仪器检测校准品、金属离子标准溶液、滴定溶液、食品检测标准物质、有机检测标准溶液、指示液、缓冲液、电导率溶液、PH标准溶液、熔点标准品、国家标准物质、比色液