Overview
Albumin refers to a group of water-soluble proteins found in blood plasma and other bodily fluids. The most well-known types are human serum albumin (HSA) and bovine serum albumin (BSA), which share similar structures but differ slightly in amino acid composition. Albumin is synthesized in the liver and plays critical roles in maintaining colloid osmotic pressure and transporting various substances throughout the body. In industrial and research contexts, albumin is extracted from blood plasma and processed into purified forms. It is widely used in pharmaceutical formulations, biotechnology applications, and diagnostic procedures due to its stability and biocompatibility.
Physical and Chemical Properties
Albumin is a globular protein with a molecular weight of approximately 66.5 kDa for human serum albumin. It consists of a single polypeptide chain with 585 amino acids and 17 disulfide bonds, contributing to its stable three-dimensional structure. The protein is highly soluble in water and exhibits remarkable heat stability, remaining soluble even after heating to 60°C. One of albumin's key chemical properties is its ability to bind and transport a wide range of molecules, including fatty acids, hormones, bilirubin, and various drugs. This binding capacity stems from multiple hydrophobic pockets in its structure. The protein also contributes significantly to blood's buffering capacity due to its numerous charged amino acid residues.
Main Applications
In the pharmaceutical industry, human serum albumin is used as a stabilizer in vaccines and therapeutic proteins, and as a volume expander in treatments for shock or burns. Its ability to bind and transport drugs makes it valuable for drug delivery systems. In biotechnology, bovine serum albumin is commonly used as a blocking agent in immunoassays and as a nutrient in cell culture media. The food industry utilizes albumin as a foaming and gelling agent, particularly in processed foods. In research laboratories, albumin serves as a standard for protein quantification assays and as a carrier protein in various biochemical applications. Diagnostic applications include its use in clinical tests for liver function and nutritional status assessment.
Safety and Storage
While generally considered safe, albumin products derived from human or animal sources must be properly processed to eliminate potential pathogens. Allergic reactions, though rare, can occur with human-derived products. Proper handling includes wearing gloves and eye protection when working with powdered forms to prevent inhalation or contact with mucous membranes. For storage, albumin should be kept in airtight containers at 2-8°C. Lyophilized forms are more stable than liquid preparations. Freezing should be avoided as it can cause protein denaturation. When reconstituting, use sterile water or buffer and avoid vigorous shaking to prevent foaming and protein damage. Always check expiration dates as albumin can degrade over time.
B2B Procurement Guide
When sourcing albumin for commercial or research purposes, clearly specify the required grade (e.g., pharmaceutical, reagent, or food grade) and purity level. Consider whether human, bovine, or recombinant albumin best suits your application, as each has different regulatory requirements and performance characteristics. For pharmaceutical applications, ensure the supplier provides appropriate documentation including Certificate of Analysis, origin tracing, and viral safety data. Bulk purchases may require negotiation of custom purity specifications or packaging. Lead times can vary significantly depending on the source and processing method, so plan procurement accordingly. Always verify the supplier's quality certifications and track record in your specific application area.
Related Manufacturers
- 主营：ELISA试剂盒、PCR试剂盒、生化试剂盒、蛋白、抗体、细胞、检测试剂盒
- 主营：矿用油浸枕木
- 主营：ELISA试剂盒、PCR试剂盒、科研试剂
- 主营：质构仪、滴点仪、粘度仪、色度仪、水分仪、硬度仪、四球机、密度计、粘度计、自燃点仪、凝点倾点仪、闪点仪、馏程仪、沸程仪、油脂氧化稳定性仪、烟点仪、酸值仪、结晶点
- 主营：肝配蛋白A受体1、试剂盒、ELISA试剂盒、ELISA检测试剂盒
- 主营：试剂盒、elisa试剂盒、细胞、pcr试剂盒
- 主营：酶cγ链、α2巨球、素d合成、纤连蛋白、抗组蛋白、蛋白样环、敏感蛋白、蛋白重链、乳球蛋白、蛋白激酶、钙调蛋白、肌醇抗体、牛骨钙素、金属肽酶、钩端螺旋、高血糖素、小鼠α1抗、ELISA试剂盒、pcr检测试剂、生化检测试剂
- 主营：ELISA试剂盒、PCR试剂盒、生化试剂盒、蛋白、抗体、细胞
- 主营：科研试剂盒、酶免试剂盒、elisa试剂盒、人肝配蛋白A受体1、细胞、生物试剂、进口ELISA试剂盒、PCR试剂盒、生化测试盒
- 主营：肝配蛋白A受体1、elisa试剂盒
- 主营：试剂盒、同源物、粘液素、脂蛋白、合蛋白、蛋白酶、凝蛋白、抑制素、亲环素、保护素、信号素、胞色素、脂肪酶、末端肽、磷脂酶、变位酶、抑制剂、脱水酶、抑制物、激活肽、连接酶、样激酶、解氨酶、恒温箱、利钠肽
- 主营：Elisa试剂盒、检测试剂盒、人elisa试剂盒、肝配蛋白A受体5、鼠elisa试剂盒、PCR检测试剂盒、生物试剂盒
- 主营：人肝配蛋白A受体1、Elisa试剂盒、检测试剂盒
- 主营：基质胶、试剂盒、细胞株、重组蛋白、脑类器官、成体干细胞、细胞培养基
- 主营：elisa试剂盒、人elisa试剂盒、小鼠elisa试剂盒、人肝配蛋白A5、大鼠elisa试剂盒、植物elisa试剂盒、鱼elisa试剂盒、猪elisa试剂盒、牛elisa试剂盒、鸡elisa试剂盒、兔elisa试剂盒、犬elisa试剂盒