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Adamantylformamide

Updated: 2026-07-19

Overview

Adamantane-1-carboxamide is a chemical compound derived from adamantane, a rigid, diamond-like hydrocarbon structure. It is primarily used as an intermediate in pharmaceutical research and chemical synthesis. The compound's unique structure imparts high thermal stability and makes it valuable in the development of drugs and other specialized chemicals. Due to its rigid molecular framework, Adamantane-1-carboxamide is often employed in the design of bioactive molecules. Its applications span across various fields, including medicinal chemistry and materials science, where its stability and predictable reactivity are highly advantageous.

Physical and Chemical Properties

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Adamantane-1-carboxamide is a white to off-white crystalline powder with a melting point of approximately 300-305°C. It is slightly soluble in water but dissolves well in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol. The compound exhibits high thermal stability due to its adamantane backbone, which resists decomposition under standard conditions. The molecular weight of Adamantane-1-carboxamide is 179.26 g/mol, and its rigid structure contributes to its low solubility in polar solvents. These properties make it suitable for applications requiring stable and predictable chemical behavior.

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Main Applications

Adamantane-1-carboxamide is primarily used as an intermediate in pharmaceutical research. Its rigid structure is advantageous in the design of drugs targeting neurological and infectious diseases. The compound is also explored in materials science for creating high-performance polymers and coatings. In addition to pharmaceuticals, Adamantane-1-carboxamide finds use in chemical synthesis as a building block for more complex molecules. Its stability and reactivity make it a valuable tool for researchers developing novel compounds with specific properties.

Safety and Storage

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Adamantane-1-carboxamide should be handled with care to avoid inhalation or skin contact. Personal protective equipment, including gloves and safety goggles, is recommended when working with this compound. It should be stored in a cool, dry place away from light and moisture to maintain its stability. In case of exposure, rinse affected areas with plenty of water and seek medical attention if necessary. Proper disposal methods should be followed to minimize environmental impact, adhering to local regulations for chemical waste.

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B2B Procurement Guide

When procuring Adamantane-1-carboxamide, it is essential to verify the supplier's credentials and request certificates of analysis (CoA) to ensure product purity and quality. Material safety data sheets (MSDS) should also be provided to confirm safe handling and storage procedures. Prices for Adamantane-1-carboxamide typically range from $100 to $300 per gram, depending on purity and supplier. Bulk purchases may offer cost savings, but buyers should ensure the supplier can meet their specific requirements and delivery timelines.

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