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7-Hydroxy-4'-methoxyflavone

Updated: 2026-07-15

Overview

7-Hydroxy-4'-methoxyflavone is a flavonoid compound belonging to the flavone subclass. Flavonoids are widely studied for their potential health benefits, including antioxidant and anti-inflammatory properties. This particular compound is of interest in pharmaceutical and biochemical research due to its structural features and potential bioactive effects. Flavonoids like 7-Hydroxy-4'-methoxyflavone are commonly found in plants and are known for their role in plant defense mechanisms. Synthetic versions are often used in research to study their effects on human health, making them valuable in the development of nutraceuticals and pharmaceuticals.

Physical and Chemical Properties

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7-Hydroxy-4'-methoxyflavone is a yellow to pale yellow crystalline powder with a molecular weight of 268.26 g/mol. It is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) but has limited solubility in water. The compound has a melting point range of approximately 200-220°C, which is typical for flavonoid derivatives. The molecular structure includes a hydroxy group at the 7-position and a methoxy group at the 4'-position, which influence its reactivity and biological activity. These functional groups make it a subject of interest in studies focusing on structure-activity relationships in flavonoids.

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Main Applications

The primary application of 7-Hydroxy-4'-methoxyflavone is in pharmaceutical and biochemical research. It is used as a reference standard in studies investigating the biological activities of flavonoids, such as antioxidant, anti-inflammatory, and anticancer effects. In addition to research, this compound may be explored for use in nutraceuticals and dietary supplements. Its potential health benefits make it a candidate for further development in the functional food and supplement industries, though clinical applications are still under investigation.

Safety and Storage

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7-Hydroxy-4'-methoxyflavone should be handled with care, using appropriate personal protective equipment (PPE) such as gloves and lab coats. Avoid inhalation or ingestion, as the compound's safety profile in humans is not fully established. For storage, keep the compound in a cool, dry place away from light and moisture to prevent degradation. Sealed containers under inert gas (e.g., nitrogen) may be recommended for long-term storage to maintain stability and purity.

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B2B Procurement Guide

When procuring 7-Hydroxy-4'-methoxyflavone, it is essential to verify the supplier's credentials and the purity of the compound. Request a Certificate of Analysis (COA) to confirm the product's specifications, including purity, solubility, and other relevant parameters. Prices can vary significantly based on purity and supplier, with reference prices ranging from approximately $50 to $200 per gram. Bulk purchases may offer cost savings, but ensure the supplier can meet quality and consistency standards. Consider working with specialized chemical suppliers with expertise in flavonoid compounds.

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