Overview
7-Bromoindole is a brominated heterocyclic compound derived from indole, a structure prevalent in many biologically active molecules. It is widely utilized as an intermediate in pharmaceutical and agrochemical synthesis. The bromine substitution at the 7-position makes it a valuable building block for further chemical modifications. This compound is particularly significant in medicinal chemistry, where it serves as a precursor for drugs targeting various therapeutic areas. Its stability and reactivity profile make it a preferred choice for researchers and industrial chemists alike.
Physical and Chemical Properties
7-Bromoindole appears as an off-white to light yellow crystalline powder with a molecular weight of 196.05 g/mol. It has a melting point of approximately 80-82 °C and is soluble in common organic solvents like ethanol, methanol, and DMSO, but only slightly soluble in water. The bromine atom at the 7-position enhances the compound's electrophilic character, making it reactive toward nucleophilic substitution reactions. This property is exploited in synthetic chemistry to create more complex molecules. The compound's stability under standard conditions allows for easy handling and storage.
Main Applications
7-Bromoindole is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is a key building block for active pharmaceutical ingredients (APIs) targeting neurological disorders, cancer, and infectious diseases. In agrochemicals, it contributes to the development of pesticides and herbicides. Additionally, it finds use in academic and industrial research for exploring new chemical entities and reaction pathways. Its versatility makes it indispensable in organic synthesis laboratories.
Safety and Storage
7-Bromoindole should be handled with care to avoid skin and eye contact, as it may cause irritation. Proper personal protective equipment (PPE), including gloves and goggles, is recommended. Ensure adequate ventilation when working with this compound. Storage should be in a cool, dry place, away from light and moisture to prevent degradation. Keep the container tightly sealed and labeled appropriately. In case of spillage, use appropriate absorbent materials and dispose of them according to local regulations.
B2B Procurement Guide
When procuring 7-Bromoindole, verify the CAS number (10075-50-0) to ensure product authenticity. Purity levels (typically 95-98%) should align with your application requirements. Reliable suppliers often provide certificates of analysis (CoA) for quality assurance. Bulk purchases may require custom synthesis, so plan ahead to account for lead times. Prices vary based on quantity and purity, with reference ranges commonly between $50-$200 per gram. Establish long-term relationships with reputable suppliers to ensure consistent quality and availability.
Related Manufacturers
- 主营：6-二羟基吲哚、磷钼酸、艾拉莫德中间体、7-去氢胆固醇、甲基丙二酸、光引发剂、苯芴醇、溴芬酸钠中间体、樟脑醌、钼酸钾、丝素蛋白、盐酸胍、β-丙氨酸甲酯盐酸盐、聚二羟基吲哚、甘氨胆酸钠盐、半叶素、胆固醇、2-辛基十二醇、蛋白酶K、D-荧光素钾盐、光引发剂LAP、BIS-TRIS、甲基丙烯酸氧杂环丁烷
- 主营：离子液体、阻燃剂、咪唑、催化剂、乙酰丙酮钴、正丁醇锆、四氟硼酸锂、香兰基丁醚、氟化物、全氟辛基三甲氧基硅烷、丙酮肟、双酚E型氰酸酯、叔丁基乙烯基醚、钯碳催化剂、钛硅分子筛、硫酸烟酰苯胺、丙酮缩氨基硫脲
- 主营：石油醚、四氢噻吩、顺酐、苯酐
- 主营：乙二醇、二甲基亚砜、丙二醇、溴吲哚、精对苯二甲酸、己二酸、聚乙烯醇、聚乙二醇、木质素、甘油、三甘醇、己内酰胺、叔十二硫醇、白油、对苯二甲酸二甲酯、4-丁二醇
- 主营：甘氨酸、甘氨酰、胰酵素、7溴吲哚、蒽甲酯、喹烯酮、黄蒿油、十五醛、碳酸镧、酰氨酸、芹菜酮、赖氨酸、980卡波、香气醇、百部酮、海蓝腈、高哌嗪、氯戊烷、苯二甲、姜黄素、三氮唑、雌三醇、溴氯苯、橙花素、纯吲哚、抗氧剂
- 主营：聚乙烯亚胺、三甘醇二异辛酸酯3G8、三硫代碳酸钠40%、5溴7氮杂吲哚、TS-1钛硅分子筛、六氯环三磷腈、5-甲基靛红、烷基苯磺酸酯、苯基次磷酸钠、甲巯咪唑、吡啶硫酮锌、焦磷酸哌嗪、热敏材料、油酸甲酯、曲酸
- 主营：三硫代碳酸钠、红色素-16、聚乙烯亚胺、溴吲哚满二酮、三乙二醇二异辛酸酯、巯基苯并噻唑钠、L-丙交酯、乙交酯、石油酯-T50、多元醇苯甲酸酯、热压敏染料、光稳定剂、高分子降解材料
- 主营：有机原料、中间体、香精香料、溴吲哚、催化剂、有机硅、表面活性剂
- 主营：化学品、香精香料、试剂、溴吲哚、中间体、有机硅、橡胶树脂、催化剂、纳米材料
- 主营：6-二羟基吲哚、二羟基吲哚啉氢溴酸、水解角蛋白、7-去氢胆固醇、石胆酸钠盐、熊去氧胆酸钠盐、2-辛基十二醇、2-巯基噻唑啉、2-巯基苯并咪唑、苯基周位酸(8-苯胺、L-丙交酯、半叶素、乙烯利、环丙磺酰胺、苄氧基胺盐酸盐、1-氨基环丙烷羧酸、4-联苯甲醇丙烯酸酯、4-羟乙烯基氧基二苯、咪鲜胺、可比落、乙交酯、D(+)-丙交酯
- 主营：抗氧剂、氧化剂、紫外线吸收剂、138937、荧光增白剂、催化剂、还原剂、缩合剂、光引发剂、酶制剂、成核剂、生物缓冲液、表面活性剂、检测试剂、光电材料中间体、改性剂、指示剂、多肽、染料中间体、固醇系列、酶溶液
- 主营：蓬松剂、异辛醇、化妆品、异辛酸、护发素、二乙二醇、反应试剂、双羟乙基、三乙醇胺、苯磺酸钠、粘合剂涂料、酰胺丙基三、表面活性剂、三甲基氯化铵、阳离子纤维素、甲基葡萄糖苷、n-甲基吡咯烷酮
- 主营：橙黄Ⅳ、纳米二氧化硅、二硝基苯甲酸、Ethyl7、丁基四氟硼酸
- 主营：乙二醇二甲基丙烯酸酯、中间体、发光材料、苯磺酸钠、UV单体、丙烯酸叔丁基氨基乙酯、丁二醇二甲基丙烯酸酯、抗氧化剂、4-二甲苯磺酸、5-羟甲基糠醛、5-硝基水杨酸、3-硝基水杨酸、吡咯喹啉醌酸、对羟基苯乙酮、间甲基二苯胺、4-甲基愈创木酚、甲基环戊烯醇酮
- 主营：壬二酸、羟乙基、三胜肽、302776-68-7、玻色因、依克多因、抗坏血酸、谷胱甘肽、苯甲酸己酯、葡糖基芦丁、紫外吸收剂、辛氧基甘油、生物素三肽、乙酰基四肽、棕榈酰三肽、肉豆蔻酰五肽、植物油脂肪酸、氨基羟苯甲酰、紫外线吸收剂、维生素c乙基醚、二氢燕麦生物碱、苯乙基间苯二酚、水杨酸乙基己酯、乙基己基三嗪酮