Overview
6-Methylnicotinic Acid is a derivative of nicotinic acid, featuring a methyl group at the 6-position of the pyridine ring. It is widely used as an intermediate in pharmaceutical synthesis and chemical research. The compound is known for its stability and compatibility with various reaction conditions, making it valuable in organic chemistry. Its applications extend to the production of active pharmaceutical ingredients (APIs) and specialty chemicals. The demand for 6-Methylnicotinic Acid is driven by its role in synthesizing compounds with therapeutic potential.
Physical and Chemical Properties
6-Methylnicotinic Acid appears as a white to off-white crystalline powder with a molecular weight of 137.14 g/mol. It has a melting point of approximately 170-175°C and is soluble in water and common organic solvents like ethanol. The compound exhibits weak acidic properties due to the carboxyl group. Under standard conditions, it is stable and does not react violently with other substances. However, it should be handled with care to avoid decomposition at high temperatures or exposure to strong oxidizing agents.
Main Applications
The primary use of 6-Methylnicotinic Acid is in the pharmaceutical industry, where it serves as a building block for APIs. It is also employed in chemical research for synthesizing novel compounds with potential biological activity. Additionally, it may be used in agrochemicals and specialty chemicals. In drug development, this compound is valued for its ability to modify the pharmacokinetic properties of molecules. Its derivatives are explored for their therapeutic effects, including anti-inflammatory and antimicrobial activities.
Safety and Storage
6-Methylnicotinic Acid should be stored in a cool, dry place away from direct sunlight to prevent degradation. Proper ventilation is recommended when handling the compound to avoid inhalation of dust. Personal protective equipment, such as gloves and goggles, should be worn to minimize skin and eye contact. In case of accidental exposure, rinse affected areas with plenty of water and seek medical advice if irritation persists. The compound is not highly toxic but should be handled with standard laboratory precautions to ensure safety.
B2B Procurement Guide
When procuring 6-Methylnicotinic Acid, buyers should prioritize suppliers with certifications such as ISO or GMP to ensure quality and consistency. Purity levels, typically ranging from 98% to 99%, should be verified through certificates of analysis (CoA). Bulk purchases may offer cost advantages, but storage capacity should be considered. It is advisable to request samples for testing before large-scale orders. Additionally, buyers should assess logistics options, including shipping conditions and lead times, to align with production schedules.
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