Overview
6-Methoxyflavanone is a synthetic flavanone derivative characterized by a methoxy group at the 6-position of the flavanone structure. It is primarily utilized in pharmaceutical research and organic synthesis due to its role as an intermediate in the production of bioactive compounds. Flavanones are a subclass of flavonoids, which are widely studied for their potential biological activities. The methoxy substitution in 6-methoxyflavanone enhances its lipophilicity and may influence its interaction with biological targets, making it valuable for drug discovery and development.
Physical and Chemical Properties
6-Methoxyflavanone appears as a pale yellow to white crystalline powder with a melting point of approximately 120-122°C. It is soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO) but exhibits poor solubility in water. The molecular weight of 6-methoxyflavanone is 254.28 g/mol, and its structure consists of a flavanone backbone with a methoxy group at the 6-position. This modification can affect its chemical reactivity and physical properties, making it suitable for specific synthetic applications.
Main Applications
6-Methoxyflavanone is primarily used as an intermediate in pharmaceutical research, particularly in the synthesis of flavonoid-based drugs. Its structure serves as a scaffold for developing compounds with potential antioxidant, anti-inflammatory, or anticancer properties. In addition to pharmaceutical applications, 6-methoxyflavanone is employed in biochemical research to study flavonoid metabolism and enzyme interactions. Its role as a reference standard in analytical chemistry further underscores its importance in quality control and method validation.
Safety and Storage
6-Methoxyflavanone should be handled with appropriate personal protective equipment, including gloves and safety goggles, to avoid skin contact or inhalation. It is recommended to work in a well-ventilated area or under a fume hood. For storage, keep the compound in a tightly sealed container away from light, moisture, and extreme temperatures. Proper labeling and segregation from incompatible substances are essential to maintain its stability and prevent contamination.
B2B Procurement Guide
When procuring 6-methoxyflavanone, B2B buyers should prioritize suppliers that provide certificates of analysis (COA) to verify purity and identity. Key specifications to confirm include CAS number (959-14-8), molecular formula (C16H14O3), and melting point range. Bulk purchases may offer cost advantages, but buyers should assess storage capabilities to ensure product integrity. Lead times and supplier reliability are also critical factors, especially for time-sensitive research projects. Comparing multiple suppliers can help secure competitive pricing and quality assurance.
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