Overview
6-Hydroxywogonin is a naturally occurring flavonoid isolated from Scutellaria species, such as Scutellaria baicalensis. With 98% purity, it is a standardized compound used primarily in research and pharmaceutical development. Its molecular structure features a hydroxyl group at the 6-position, enhancing its bioactivity compared to its parent compound, wogonin. This compound has garnered attention for its potential therapeutic effects, including anti-inflammatory, antioxidant, and anticancer properties. Laboratories and manufacturers value high-purity 6-hydroxywogonin for reproducibility in studies and formulation consistency.
Physical and Chemical Properties
6-Hydroxywogonin is a yellow crystalline powder with a molecular weight of 300.26 g/mol. It exhibits moderate solubility in organic solvents like DMSO and methanol but is poorly soluble in water. The compound is stable under recommended storage conditions but may degrade if exposed to prolonged light or humidity. Key spectroscopic properties include UV-Vis absorption maxima around 275 nm and 335 nm, useful for analytical quantification. Its melting point range (200-220°C) helps distinguish it from related flavonoids. The 98% purity grade ensures minimal impurities, critical for experimental accuracy.
Main Applications
In pharmaceutical research, 6-hydroxywogonin is investigated for its role in modulating cellular pathways, particularly those involving oxidative stress and inflammation. Studies suggest potential applications in neurodegenerative diseases, cardiovascular health, and oncology. Nutraceutical formulations may incorporate this compound for its antioxidant benefits, though clinical validation is ongoing. Additionally, it serves as a reference standard in chromatographic analysis and quality control for herbal extracts.
Safety and Storage
While 6-hydroxywogonin is not classified as highly hazardous, standard laboratory precautions should be followed. Use gloves and eye protection to avoid irritation. Store the powder in a tightly sealed container at -20°C to prevent degradation. Long-term stability is ensured under inert gas (e.g., argon) in amber vials. Dispose of waste according to local regulations for organic compounds. Always consult the Safety Data Sheet (SDS) for specific handling instructions.
B2B Procurement Guide
When sourcing 6-hydroxywogonin, prioritize suppliers who provide certified purity analysis (e.g., HPLC-UV or LC-MS). Batch-specific Certificates of Analysis (COA) should detail residual solvents and heavy metals. Bulk buyers should negotiate lead times, as synthesis or purification may require weeks. Consider suppliers with ISO 9001 or GMP certification for consistency. Pricing varies based on quantity and purity; samples are advisable for quality verification. International shipments may require special packaging to maintain stability during transit.
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