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6-Aminomethyl-3-cyanopyridine

Updated: 2026-07-15

Overview

6-Aminomethyl-3-cyanopyridine is a heterocyclic organic compound with a pyridine backbone substituted with an aminomethyl group at the 6-position and a cyano group at the 3-position. It is primarily used as an intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical industry. The compound is known for its versatility in organic synthesis, enabling the introduction of functional groups that are crucial for the development of active pharmaceutical ingredients (APIs). Its molecular structure allows for further modifications, making it valuable in medicinal chemistry.

Physical and Chemical Properties

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6-Aminomethyl-3-cyanopyridine typically appears as a white to off-white crystalline powder. It is soluble in common organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO), which facilitates its use in various chemical reactions. The compound's molecular weight is 133.15 g/mol, and its exact melting and boiling points are not widely documented. However, its stability under standard laboratory conditions makes it suitable for storage and handling in controlled environments.

Main Applications

The primary use of 6-Aminomethyl-3-cyanopyridine is as a building block in pharmaceutical synthesis. It serves as a precursor for the development of drugs targeting neurological and cardiovascular diseases. Additionally, it finds applications in agrochemical research, where it is used to synthesize compounds with potential pesticidal or herbicidal activity. Its role in organic synthesis extends to the production of specialty chemicals and fine chemicals.

Safety and Storage

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Handling 6-Aminomethyl-3-cyanopyridine requires adherence to standard laboratory safety protocols. Personal protective equipment (PPE), including gloves and goggles, should be worn to prevent skin and eye contact. The compound should be stored in a cool, dry place, away from direct sunlight and moisture. Proper ventilation is recommended to minimize inhalation risks. In case of exposure, immediate washing with water and seeking medical advice are advised.

B2B Procurement Guide

When procuring 6-Aminomethyl-3-cyanopyridine, B2B buyers should prioritize suppliers who provide comprehensive documentation, including a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). These documents ensure the product meets purity and safety standards. Buyers should also consider the supplier's reputation, production capacity, and ability to provide consistent quality. Bulk purchases may offer cost advantages, but it's essential to verify storage conditions to maintain product integrity.

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