Overview
5,6-Dimethoxyindan-1-one is an organic compound belonging to the indanone class. It is widely used as an intermediate in the synthesis of pharmaceuticals and other fine chemicals. The compound features a fused benzene and cyclopentanone ring system with methoxy substituents at the 5 and 6 positions. Its structural characteristics make it a valuable building block in medicinal chemistry, particularly for the development of compounds with potential biological activity. The presence of methoxy groups enhances its reactivity and solubility in organic solvents, facilitating its use in various synthetic pathways.
Physical and Chemical Properties
5,6-Dimethoxyindan-1-one typically appears as a white to off-white crystalline powder. It has a molecular weight of 192.21 g/mol and a melting point range of approximately 110-115°C. The compound is soluble in common organic solvents such as ethanol, methanol, and acetone but exhibits limited solubility in water. The methoxy groups attached to the aromatic ring influence its electronic properties, making it a versatile intermediate in organic synthesis. The compound is relatively stable under normal storage conditions but may degrade when exposed to extreme temperatures, light, or moisture. Proper handling and storage are essential to maintain its integrity.
Main Applications
The primary application of 5,6-Dimethoxyindan-1-one is as an intermediate in pharmaceutical synthesis. It serves as a key building block for the production of various bioactive molecules, including potential drugs targeting neurological and cardiovascular diseases. In addition to pharmaceuticals, the compound is used in academic and industrial research for the development of novel organic compounds. Its reactivity and structural features make it suitable for use in cross-coupling reactions, cyclizations, and other synthetic transformations. The demand for this compound is driven by its utility in creating complex molecular architectures.
Safety and Storage
When handling 5,6-Dimethoxyindan-1-one, it is essential to follow standard laboratory safety protocols. The compound should be used in a well-ventilated area, and direct contact with skin, eyes, or respiratory system should be avoided. Personal protective equipment (PPE), including gloves and safety goggles, is recommended. Storage conditions are critical to maintaining the compound's stability. It should be kept in a tightly sealed container, away from light, moisture, and extreme temperatures. Long-term storage in a cool, dry environment is advisable to prevent degradation. Proper disposal methods should be followed in accordance with local regulations.
B2B Procurement Guide
For B2B buyers, sourcing 5,6-Dimethoxyindan-1-one requires careful consideration of supplier reliability, product purity, and pricing. Reputable suppliers should provide certificates of analysis (CoA) to verify the compound's purity and quality. Bulk purchases may offer cost advantages, but buyers should assess storage capabilities to ensure product integrity. Procurement professionals should also evaluate lead times, shipping conditions, and regulatory compliance. Establishing long-term relationships with trusted suppliers can ensure consistent quality and availability. Buyers are encouraged to request samples for testing before committing to large orders.
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