Overview
5-Methoxyflavanone is a flavonoid derivative belonging to the flavanone class of compounds. It is structurally characterized by a flavone backbone with a methoxy group at the 5-position. This compound is primarily used in pharmaceutical research and organic synthesis due to its potential bioactive properties. Flavonoids like 5-Methoxyflavanone are widely studied for their antioxidant, anti-inflammatory, and potential therapeutic effects. The compound serves as an important intermediate in the synthesis of more complex molecules for medicinal chemistry applications.
Physical and Chemical Properties
5-Methoxyflavanone appears as a pale yellow to white crystalline powder with a melting point range of 120-122°C. It is soluble in common organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), but has limited solubility in water. The molecular structure features a 15-carbon skeleton arranged in three rings, with the methoxy group at position 5 contributing to its specific chemical behavior. Its UV absorption characteristics make it useful in analytical applications. The compound exhibits typical flavonoid reactivity patterns, including susceptibility to oxidation under certain conditions.
Main Applications
In pharmaceutical research, 5-Methoxyflavanone serves as a key intermediate for developing potential therapeutic agents. It's particularly valuable in studies exploring structure-activity relationships of flavonoid compounds. The compound also finds use in organic synthesis as a building block for more complex molecules. Some research suggests potential applications in cosmetic formulations due to its structural similarity to other bioactive flavonoids. Additionally, it's employed as a reference standard in analytical chemistry for flavonoid identification and quantification.
Safety and Storage
5-Methoxyflavanone should be handled with appropriate personal protective equipment, including gloves and eye protection. While not classified as extremely hazardous, it may cause irritation upon contact with skin or eyes. Proper storage requires protection from light and moisture in a tightly sealed container. The compound should be kept in a cool, well-ventilated area away from incompatible substances. Shelf life is typically several years when stored correctly, though purity should be verified before use in sensitive applications.
B2B Procurement Guide
When sourcing 5-Methoxyflavanone commercially, prioritize suppliers who provide detailed certificates of analysis (COA) including purity information (typically 95-99% by HPLC). Technical specifications should include information about residual solvents and heavy metal content. For research applications, small quantity packaging (1g to 100g) is commonly available, while bulk quantities may require special ordering. Consider suppliers with GMP or ISO certification for pharmaceutical-grade material. Lead times can vary significantly depending on source and quantity, so plan procurement accordingly.
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