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5-Hydroxyvanillin

Updated: 2026-08-05

Overview

5-Hydroxyvanillin is a derivative of vanillin, commonly used in the pharmaceutical and flavoring industries. It is a white crystalline powder with antioxidant properties and a mild vanilla-like odor. The compound is synthesized through chemical processes and serves as an intermediate in various applications. Its molecular structure includes a hydroxyl group at the fifth position, enhancing its solubility in polar solvents. This makes it suitable for use in formulations requiring water solubility. The compound is often preferred for its stability and compatibility with other ingredients.

Physical and Chemical Properties

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5-Hydroxyvanillin exhibits a melting point of approximately 120-122°C, making it stable under moderate temperatures. It is soluble in ethanol, methanol, and water, which facilitates its use in liquid formulations. The compound's antioxidant properties contribute to its role in preserving products. The presence of a hydroxyl group in its structure enhances its reactivity, allowing it to participate in various chemical reactions. This property is exploited in pharmaceutical synthesis, where it serves as a building block for more complex molecules. Its mild odor also makes it suitable for flavoring applications.

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Main Applications

In the pharmaceutical industry, 5-Hydroxyvanillin is used as an intermediate in the synthesis of drugs. Its antioxidant properties make it valuable in formulations aimed at reducing oxidative stress. The compound is also employed in cosmetics for its stabilizing effects. The flavoring industry utilizes 5-Hydroxyvanillin for its vanilla-like aroma. It is often incorporated into food products and beverages to enhance flavor profiles. Its solubility in water and alcohol ensures easy integration into various formulations.

Safety and Storage

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5-Hydroxyvanillin should be handled with care to avoid inhalation or direct contact with skin and eyes. Protective gear, such as gloves and goggles, is recommended during handling. The compound should be stored in a cool, dry place away from light and moisture to maintain its stability. Proper storage conditions prevent degradation and ensure the compound retains its efficacy. Suppliers typically provide safety data sheets (SDS) detailing handling and storage guidelines. Compliance with these guidelines is essential for safe usage.

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B2B Procurement Guide

When procuring 5-Hydroxyvanillin, buyers should verify the CAS number (1453-93-6) to ensure product authenticity. Purity levels should be confirmed through certificates of analysis (CoA) provided by suppliers. It is advisable to source from reputable manufacturers with relevant certifications. Price ranges vary depending on quantity and supplier. Bulk purchases may offer cost advantages, but buyers should balance cost with quality considerations. Procurement professionals should also evaluate logistics and storage capabilities to maintain product integrity during transit.

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