Overview
5-Hydroxy-2-hydroxymethylpyridine is an organic compound with a pyridine backbone substituted with hydroxyl and hydroxymethyl groups. It serves as a key intermediate in pharmaceutical synthesis and other chemical processes. The compound is known for its stability and reactivity, making it valuable in various industrial applications. Its molecular structure allows for further functionalization, which is particularly useful in the development of active pharmaceutical ingredients (APIs). The compound is typically synthesized through controlled chemical reactions involving pyridine derivatives.
Physical and Chemical Properties
5-Hydroxy-2-hydroxymethylpyridine appears as a white to light yellow crystalline powder with a melting point range of 140-145°C. It is soluble in water and most organic solvents, which facilitates its use in various reaction conditions. The compound is hygroscopic, requiring careful handling to prevent moisture absorption. Its stability under normal storage conditions makes it a reliable reagent for laboratory and industrial use. However, prolonged exposure to air or moisture may degrade its quality, necessitating proper storage and handling protocols.
Main Applications
This compound is primarily used as an intermediate in the synthesis of pharmaceuticals, including antiviral and antibacterial agents. Its reactive hydroxyl and hydroxymethyl groups make it a versatile building block for more complex molecules. Additionally, it finds applications in agrochemicals and specialty chemicals. Researchers also explore its potential in material science, particularly in the development of functional polymers and coatings.
Safety and Storage
5-Hydroxy-2-hydroxymethylpyridine should be handled with care to avoid inhalation or skin contact. Personal protective equipment, including gloves and goggles, is recommended during handling. The compound is not highly toxic but may cause irritation upon contact. Storage should be in a cool, dry place, preferably in airtight containers to prevent moisture absorption. Proper labeling and segregation from incompatible substances are essential to maintain safety and product integrity.
B2B Procurement Guide
When procuring 5-Hydroxy-2-hydroxymethylpyridine, buyers should verify the supplier's credentials and request a Certificate of Analysis (COA) to ensure purity and quality. Bulk purchases may offer cost advantages, but storage capacity should be considered to prevent degradation. It's advisable to establish long-term relationships with reputable suppliers to ensure consistent quality and reliable delivery. Buyers should also stay informed about market trends and regulatory changes affecting the availability and pricing of this chemical.
Related Manufacturers
- 主营：磷钼酸、艾拉莫德中间体、光引发剂、6-二羟基吲哚、甲基丙二酸、β-丙氨酸甲酯盐酸盐、聚二羟基吲哚、7-去氢胆固醇、2-辛基十二醇、D-荧光素钾盐、BIS-TRIS、甲基丙烯酸氧杂环丁烷、苯芴醇、溴芬酸钠中间体、樟脑醌、钼酸钾、丝素蛋白、盐酸胍、甘氨胆酸钠盐、半叶素、胆固醇、蛋白酶K、光引发剂LAP
- 主营：杂环化合物、丙烯酸系列
- 主营：氯菊酯、转移剂、聚酯树脂、对羟基苯甲醚、二甲氧基、驱蚊原液、食品香料、缩水甘油酯、蚊香增效剂、丙烯酸缩水、环氧稀释剂、硅烷偶联剂、超疏水材料、对甲氧基苯酚、乙烯基双封头、苯基缩水甘油醚
- 主营：固体酸催化剂、重组胶原蛋白、硅油、t-BAMBP萃取剂、特种硅油、聚硅氮烷、硼酸铝晶须、碳化硅晶须、全氟三丁胺
- 主营：粘结剂、阻燃剂、絮凝剂、3584-23-4、羟乙基、l-丙交酯、引发剂、哌啶基、封端剂、乙交酯、抗菌剂、交联剂、肌肽锌、增亮剂、干燥剂、润滑剂、护发剂、粘合剂、对位酯、阻聚剂、稀释剂、偶联剂、分散剂、中间体、丙烯酸锌
- 主营：5-二甲基吡唑、TS-钛硅分子筛、离子液体、丙酮缩氨基硫脲、硫酸烟酰苯胺
- 主营：苯甲醛、酰亚胺、苯磺酸、cas-50-63-5、甲基硅基、盐酸羟胺、甲基乙炔、异丙基、氨基丙基、试剂医药、化学醋酸、化学试剂、苯并三唑、苄基丙酮、试剂化工、丙烯酰氯、氮杂苯并、二叔丁酯、磷酸二苯酯、化学碳酸钾、二酸二乙酯、酸二异丙酯、二咪唑羰基、中间体化工、医药中间体
- 主营：乙酸镁、并噻吩、三蝶烯、α-氟萘、羟乙基、2223-82-7、硫酸锂、二乙烯、硫酸锶、肌氨酸、嘧菌酯、碳酸镁、新癸酸、赖氨酸、多佐胺、咯菌腈、乙氧基、茚三酮、咖啡酸、氟苯基、异恶唑、喹啉黄、庚二酸、虫酰肼、吡咯并
- 主营：甘氨酸、溴化物、戊酸鈉、联吡啶、羟乙基、蒽甲酸、紫苏葶、锂电池、牛磺酸、褪黑素、磷酸铟、新癸酸、赖氨酸、溴化鏻、乙氧基、藏花醛、豆甾醇、维素酶、庚二酸、呋虫胺、丹参素、萘甲醛、槐豆胶、黄柏酮、元明粉
- 主营：莪术二酮、人参皂苷rc、自制对照品、羟基、淫羊藿次苷
- 主营：5-乙酰水杨酰胺、透明液体、巴比妥酸
- 主营：72、莪术二酮、人参皂苷rc
- 主营：正辛胺、柠檬酸、尿嘧啶、15397-15-6、119736-16-2、4-嘧啶酮、923289-21-8、152628-02-9、2346620-55-9、抗皱素、绿原酸、异丁基、三辛胺、双醚芴、姜黄素、角鲨烯、精磺胺、蒜氨酸、九甘醇、氟苯基、苯甲酰胺、比卡鲁胺、四氢嘧啶、氨基二环、麦角硫因
- 主营：35、环酸、异构十醇
- 主营：二苯胺、基嘧啶、甲苯氟、双吡啶、吡啶醛、吡啶醇、24滴、脱乙基、咯喹酮、嘧菌酯、溴苯基、氟磺隆、特戊醛、基哌嗪、氟苯基、碲化钠、酸性红、噻虫啉、三甘醇、异氯磷、茚草酮、二羧酸、三硫代碳酸钠、磷酸铁、聚酯多元醇