Overview
5-Formyl-2-furancarboxaldehyde is a furan derivative with two aldehyde functional groups, making it a versatile intermediate in organic synthesis. It is commonly used in the production of pharmaceuticals, agrochemicals, and specialty chemicals. The compound's reactivity allows it to participate in various condensation and addition reactions, enabling the synthesis of complex molecules. Due to its bifunctional nature, 5-Formyl-2-furancarboxaldehyde is particularly valuable in constructing heterocyclic compounds. Its applications extend to materials science, where it serves as a precursor for polymers and resins. The compound is typically synthesized through the oxidation of furfural or related furan derivatives.
Physical and Chemical Properties
5-Formyl-2-furancarboxaldehyde is a pale yellow to colorless liquid at room temperature. It has a molecular weight of 124.09 g/mol and a density of approximately 1.21 g/cm³. The compound is soluble in common organic solvents such as ethanol and acetone but has limited solubility in water. Its boiling point ranges between 230-240°C, and it exhibits typical aldehyde reactivity, including participation in nucleophilic addition and condensation reactions. The presence of two aldehyde groups enhances its utility as a building block in synthetic chemistry. Stability under normal conditions makes it suitable for industrial applications, though it should be protected from prolonged exposure to air and moisture.
Main Applications
The primary use of 5-Formyl-2-furancarboxaldehyde is as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its reactive aldehyde groups enable the formation of Schiff bases, which are key intermediates in drug development. The compound is also employed in the production of specialty chemicals, including dyes and fragrances. In materials science, 5-Formyl-2-furancarboxaldehyde is used to synthesize polymers and resins with enhanced thermal and mechanical properties. Its bifunctional nature allows for cross-linking, leading to durable materials. Additionally, it serves as a precursor in the manufacture of corrosion inhibitors and other industrial additives.
Safety and Storage
5-Formyl-2-furancarboxaldehyde is an irritant and should be handled with care. Proper personal protective equipment (PPE), including gloves and safety goggles, is essential when working with this compound. It should be used in well-ventilated areas to avoid inhalation of vapors. Storage conditions should prioritize cool, dry environments away from direct sunlight and oxidizing agents. Containers must be tightly sealed to prevent moisture absorption and degradation. In case of spills, absorb with inert material and dispose of according to local regulations. Always refer to the material safety data sheet (MSDS) for detailed safety instructions.
B2B Procurement Guide
When procuring 5-Formyl-2-furancarboxaldehyde, prioritize suppliers with verified certifications and a track record of quality. Request certificates of analysis (CoA) to confirm purity and consistency. Bulk purchases may offer cost savings, but ensure proper storage facilities are available to maintain product integrity. Evaluate supplier reliability by reviewing lead times, packaging options, and compliance with international standards such as ISO or GMP. Consider establishing long-term contracts with trusted suppliers to secure stable pricing and supply. For specialized applications, custom synthesis or tailored formulations may be available from certain manufacturers.
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