Overview
2,5-Dimethylphenol is an aromatic organic compound belonging to the phenol family. It features two methyl groups at the 2 and 5 positions of the benzene ring, which influence its reactivity and physical properties. Industrially, it serves as a versatile intermediate in chemical synthesis. The compound is synthesized through methylation of phenol or derived from coal tar fractions. Its moderate solubility and distinct phenolic odor make it identifiable in industrial settings. Commercial grades typically range from 95% to 99% purity, with higher purity required for pharmaceutical applications.
Physical and Chemical Properties
As a crystalline solid, 2,5-dimethylphenol exhibits typical phenolic characteristics including weak acidity (pKa ~10). Its melting point (74-76°C) allows easy handling in molten form for industrial processes. The compound's boiling point (211-212°C) indicates moderate volatility. Chemically, the hydroxyl group participates in reactions like etherification and esterification, while the aromatic ring undergoes electrophilic substitutions. The methyl groups slightly increase electron density on the ring compared to phenol, affecting reaction rates. UV-Vis spectroscopy shows absorption around 275 nm due to the aromatic system.
Main Applications
In resin production, 2,5-dimethylphenol modifies formaldehyde resins to enhance thermal stability, particularly in coatings and adhesives. The compound's antimicrobial properties make it valuable in disinfectant formulations for industrial and agricultural use. The pharmaceutical industry utilizes it as a precursor for antihypertensive drugs and antiseptics. In fragrances, it contributes smoky, medicinal notes in perfumery bases. Emerging applications include its use as a stabilizer in polymer production and as an intermediate in specialty chemical synthesis.
Safety and Storage
As a phenolic compound, 2,5-dimethylphenol requires careful handling. It is classified as harmful (Xn) under GHS, with risk phrases R22 (harmful if swallowed) and R37 (irritating to respiratory system). Skin contact may cause irritation or allergic reactions. Storage should be in tightly sealed containers, preferably steel or HDPE, away from oxidizers. Recommended storage temperature is below 30°C. Spills should be contained with inert absorbents and cleaned promptly with proper PPE. Waste disposal must comply with local regulations for phenolic compounds.
B2B Procurement Guide
Industrial buyers should prioritize suppliers with batch analysis certificates and stable production capacity. Technical specifications should confirm absence of heavy metals (Pb, Hg <10ppm) for sensitive applications. Packaging options typically include 25kg fiber drums or 200kg steel drums with polyethylene liners. For international shipments, ensure compliance with transport regulations (UN 3077 for environmental hazards). Sample testing for color, melting range, and HPLC purity is recommended before large orders. Annual contracts with price adjustment clauses help manage market volatility in aromatic chemical markets.
Related Manufacturers
- 主营：乙硫醇、环丁砜、四氢吡咯、3-羟基丙腈、二甲基亚砜、二甲基二硫醚、苯酚、四氢噻吩、四氢呋喃、三聚甲醛、氯乙酸、氯乙酸钠、偏铝酸钠、异辛烷、偏三甲苯、硬脂酸锌、邻苯二甲酸二丁酯、MIBC、苯酐、顺酐
- 主营：四氢噻吩、一乙醇胺、异辛醇、二甲基二硫、二甲基亚砜、燕化苯酚、3-乙氧基丙胺、环丁砜、异丙醚、环己酮、异辛烷、氟硼酸、三乙胺、正庚烷、马来酸酐、三乙醇胺、亚硝酸钠、鲁西甲酸、三氧化二锑
- 主营：硫酸铜、除磷剂、溶剂油、二甲基、二甲苯、双戊烯、胶黏剂、葡萄糖、正丙醇、丙三醇、环己胺、四甲苯、锂电池、无水糖、压敏胶、维生素、乙二胺、二甘醇、丁二醇、络合剂、去味剂、乙二醇、显示屏、三乙胺、纤维素、粘合剂
- 主营：化学试剂、氯金酸、卡尔费休、35、乙醇、异丙醇、药用辅料、依地酸钙钠、碳酸钠、盐酸氨丁三醇、龙胆酸、枸橼酸钠、甲醇、氢氧化钠、钴锰催化剂、硫酸锰、乙腈、色谱试剂、助剂、指示剂、醋酸锰、醋酸钴、氨丁三醇、尿素、硼酸
- 主营：甜菊糖、甘氨酸、cmc淀粉、二甲基、阿力甜、栀子红、胺鲜酯、柠檬油、韦兰胶、可可壳、增稠剂、海藻糖、辣椒精、姜精油、独活油、川芎油、海松素、软明胶、酪蛋白、麦芽粉、玉米肽、果乳糖、乳制品、龙脑油、牛磺酸、磷酸铁
- 主营：对氯间二甲苯酚、催化剂、香料/香精
- 主营：5-溴-7-氮杂吲哚、柠檬酸钠、液体溴化钙
- 主营：二甲基、苄基丙酮
- 主营：25、甲酚、抗氧剂
- 主营：正辛烷、偶氮二异丁腈、聚磷酸铵、二甲基亚砜、二氧化硒、甲醇钠、聚乙烯吡洛烷酮、叔丁醇、对苯二胺、邻苯二胺、香精、间苯二胺
- 主营：二甲基、聚苯胺、脯氨酸甲酯盐酸盐、苄基三甲基氯化铵
- 主营：阻燃剂、催化剂、水杨酸、95、二苯基、酰亚胺、正磷酸、烟酰胺、曲酸粉、氯化锌、异丙醇、化妆品、初油酸、脂肪醇、生石灰、甲基异、碳酸锌、碳酸锂、活性炭、乙二胺、三氮唑、着色剂、环己酮、防冻液、抗氧剂、亚磷酸
- 主营：抗氧剂BHT、苯磺酸、环烷酸铈、苯酚磺酸、N235 萃取剂、C272萃取剂、均苯四甲酸二酐、对苯乙烯磺酸钠、氟化铝、椰油酰胺丙基甜菜碱、甘油三苯甲酸酯
- 主营：甘氨酸、水苏糖、阻燃剂、1680-21-3、硫酸锌、硫酸锆、硫酸锂、硫酸锶、硫酸锰、铝酸锌、牛磺酸、褪黑素、磷酸铁、丙酸铵、苏云金、碳酸镁、麝香酮、肉桂醛、磷酸铝、王浆酸、椰油胺、赖氨酸、增塑剂、浸膏粉、乙氧基
- 主营：氯化锌、玻璃粉、冰醋酸、对氯间二甲苯酚、茶皂素、甘氨酸、渗透剂、棕榈酸、氯化钾、靛蓝粉、磷酸钙、eva乳液、氟化钾、堵漏王、早强剂、三甘醇、亚油酸、木质素、氟化钠、铵明矾、pvc树脂、富马酸、白糊精、壳聚糖、苯丙乳液、三乙二醇