Overview
5-Chloro-7-methyl-6-azaindole is a nitrogen-containing heterocyclic compound with applications in pharmaceuticals and agrochemicals. Its unique structure makes it a valuable intermediate in the synthesis of bioactive molecules. The compound is typically synthesized through multi-step organic reactions, and its purity is critical for end-use applications. Due to its role in drug development, 5-Chloro-7-methyl-6-azaindole is often supplied to research institutions and pharmaceutical companies. Its stability and reactivity profile make it suitable for further functionalization, enabling the creation of complex molecular architectures.
Physical and Chemical Properties
5-Chloro-7-methyl-6-azaindole is an off-white to light brown crystalline powder with a molecular weight of 166.61 g/mol. It is soluble in common organic solvents such as dimethyl sulfoxide (DMSO) and methanol, which facilitates its use in laboratory and industrial settings. The compound's heterocyclic structure includes a chlorine atom and a methyl group, which influence its reactivity. While specific melting and boiling points are not widely documented, it is known to be stable under standard storage conditions. Proper handling is essential to maintain its integrity and prevent degradation.
Main Applications
The primary use of 5-Chloro-7-methyl-6-azaindole is as an intermediate in pharmaceutical and agrochemical synthesis. It serves as a building block for active pharmaceutical ingredients (APIs) and other bioactive compounds. Its structural features allow for further modifications, making it versatile in medicinal chemistry. In agrochemicals, the compound contributes to the development of pesticides and herbicides. Its efficacy in these applications stems from its ability to interact with biological targets, though specific formulations are proprietary. Research into new applications is ongoing, particularly in the field of oncology and antimicrobial agents.
Safety and Storage
5-Chloro-7-methyl-6-azaindole should be handled with care, using appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Avoid inhalation or skin contact, as the compound may cause irritation or other adverse effects. Storage conditions are critical to maintaining the compound's stability. It should be kept in a cool, dry place, away from direct light and moisture. Sealed containers are recommended to prevent contamination and degradation. Always refer to the material safety data sheet (MSDS) for detailed safety guidelines.
B2B Procurement Guide
When procuring 5-Chloro-7-methyl-6-azaindole, buyers should prioritize suppliers with a proven track record of quality and reliability. Key considerations include purity levels (typically 95% or higher), packaging options, and compliance with regulatory standards. Request certificates of analysis (COA) and MSDS to verify product specifications. Pricing varies based on quantity and supplier, with bulk purchases often offering cost advantages. Lead times can vary, so plan procurement accordingly to avoid disruptions in production or research activities.
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